Von Hippel-Lindau (VHL) is a genetic condition involving the abnormal growth of blood vessels in some parts of the body which are particularly rich in blood vessels. It is caused by a flaw in one gene, the VHL gene, on the short arm of chromosome 3, which regulates cell growth.
Medical care for people with von Hippel-Lindau disease depends on which tumors they have. Many tumors can be removed by surgery; some do not need to be removed unless they are causing symptoms (for example, a brain tumor pressing on part of the brain). Individuals with von Hippel-Lindau need to have complete physical examinations regularly, including magnetic resonance imaging (MRI) or computed tomography (CT) scans of the brain, abdomen, and kidneys to watch for new tumors. Eye examinations should also be done regularly, since eye tumors may develop.