Pacerone

Pacerone Amiodarone-Oral Pacerone is used to treat irregular heart rhythms (arrhythmias) and to maintain a normal heart rate.

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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

pacerone Uses Pacerone is used to treat irregular heart rhythms (arrhythmias) and to maintain a normal heart rate. Storage Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include weakness, severe dizziness, unusually slow heartbeat, or fainting. Photos PACERONE PACERONE Pacerone (amiodarone) 200 mg Pacerone (amiodarone) 400 mg Pacerone (amiodarone) 100 mg How To Use Take Pacerone by mouth. It is best taken with food. However, it is more important to take amiodarone consistently, with regard to meals. Ask your pharmacist for additional information. Pacerone works best when there is a constant level of Pacerone in your body. To do this, take each dose exactly as prescribed at evenly spaced intervals throughout the day and night. Try to take each dose at the same time each day. Do not stop taking Pacerone or change the dose without first consulting your doctor. Some conditions may become worse when Pacerone is suddenly stopped or when more drug is taken than prescribed. Side Effects Also see the Warning section. Constipation, loss of appetite, bitter taste in mouth, nausea, vomiting, dizziness, trouble sleeping, headache, flushing of the face, or decreased sexual interest may occur as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor promptly. Pacerone, when used in combination with simvastatin, may infrequently cause muscle damage (which can rarely lead to a very serious condition called rhabdomyolysis). Tell your doctor immediately if you develop: muscle pain/tenderness/weakness (especially with fever or unusual tiredness). Tell your doctor immediately if any of these unlikely but serious side effects occur: coldness, sweating, unexplained weight change, enlarged thyroid gland, nervousness, uncontrolled shaking/tremor, sluggishness, loss of coordination, tingling or numbness of the hands or feet, swelling of the hands or feet, irregular pulse, vision changes (e.g., seeing halos, blurred vision, loss of vision - See Warnings), easy bruising/bleeding, persistent sore throat. Pacerone may cause skin reactions similar to a serious sunburn. Infrequently with long-term amiodarone treatment, you may develop blue-gray discoloring of the skin, particularly of the face and hands. This effect is not harmful and usually reverses, sometimes incompletely, after Pacerone is stopped. Avoiding prolonged sun exposure may help to prevent this effect. See also Precautions. In the unlikely event you have an allergic reaction to Pacerone, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Pacerone should not be used if you have certain medical conditions. Before using Pacerone, consult your doctor or pharmacist if you have: certain types of irregular heartbeats or heart rhythms (e.g., severe sinus node dysfunction resulting in marked sinus bradycardia, second or third degree atrioventricular block, bradycardia with associated syncope except when a pacemaker is used). Before using Pacerone, tell your doctor or pharmacist your medical history, especially of: liver disease, heart problems (e.g., congestive heart failure, low blood pressure), lung diseases, thyroid problems, upcoming major surgery, electrolyte problems such as low potassium or low magnesium, any allergies. Pacerone may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Pacerone may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. Pacerone is not recommended for use during pregnancy due to the potential for fetal harm. Consult your doctor for more details. Amiodarone passes into breast milk. Breast-feeding is not recommended while using Pacerone. Missed Dose If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Pacerone should not be used with the following medications because very serious interactions may occur: agalsidase beta, dofetilide, certain HIV protease inhibitors (nelfinavir, ritonavir), quinupristin/dalfopristin. If you are currently using any of these medications, tell your doctor or pharmacist before starting amiodarone. Other drugs besides amiodarone which may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, disopyramide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Before using Pacerone, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: blood thinners (e.g., warfarin), cimetidine, cyclosporine, digoxin, fentanyl, local and general anesthesia, heart medications (e.g., diltiazem, verapamil, beta-blockers such as propranolol), other HIV protease inhibitors (e.g., amprenavir, indinavir), methotrexate, phenytoin, rifampin, statins (e.g., lovastatin, simvastatin), St. John s wort. Avoid eating grapefruit or drinking grapefruit juice while being treated with Pacerone unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.

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User Medicine Opinions for pacerone

Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: M Age: 53 Location: Ohio Time Taken: 3 months Reason: stabilizer after atrial fib ablation Date: 26 September 2010 Side Effects Flushed, sick feeling all the time with upset stomach, vision/blurry Additional Thoughts Read the comments on topix---many people have died from this medication Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 91 Location: Largo, FL 33770 Time Taken: 3-4 weeks Reason: Heart problems after being hospitalized with norovirus Date: 21 March 2010 Side Effects Severely red and itchy hands and feet, and red rash on upper thighs. Additional Thoughts After additional checking, it seems Pacerone is a drug of last resort ... not sure my situation warranted it. Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: M Age: 58 Location: MISSOURI Time Taken: 3 months Reason: Atrial Fibrillation Date: 28 July 2008 Side Effects Seems to work well controlling the A-Fib. Having trouble sleeping. Belive it slows my heart too much while sleeping. Wake up with terrible pounding in chest, disorientation, short of breath. It goes away but can't get back to sleep. Additional Thoughts

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.