| aloprim |
Allopurinol is used to treat high levels of uric acid in your body. Uric acid can cause gout. This injection is usually given to people with cancer a day or two before receiving chemotherapy. Chemotherapy kills cancer cells and these dead cells can cause very high levels of uric acid in your body (tumor lysis syndrome).
- Store unmixed/powder vials at room temperature between 68 and 77 degrees F (20 and 25 degrees C).
- After mixing and further dilution with IV fluids, this product is stable for 10 hours at room temperature.
- Do not refrigerate the mixed vial or diluted solution.
- Discard any unused portion of the vial.
- If overdose is suspected, contact your local poison control center or emergency room immediately.
Allopurinol Aloprim , Zyloprim
Important message regarding Aloprim™
- Follow all directions for proper mixing and dilution with the correct IV fluids.
- If you have any questions regarding the use of Aloprim, consult your pharmacist.
- Give Aloprim by vein (IV) over approximately 30 minutes in a saline (NS) or dextrose (D5W) solution as directed by your doctor.
- The dosage and schedule is based on your medical condition and response to therapy.
- Drink plenty of water when using Aloprim.
- Do not mix Aloprim solution with any other IV fluids or medications.
- Consult your pharmacist for more information.
- Aloprim should be given 24 to 48 hours before the start of your cancer chemotherapy treatment.
- Consult your doctor.
- Before using, check this product visually for particles or discoloration.
- If either is present, do not use the liquid.
- Learn how to store and discard needles and medical supplies safely.
- Consult your pharmacist.
- Nausea, vomiting, drowsiness, and/or redness/swelling at the injection site may occur.
- If any of these effects persist or worsen, notify your doctor.
- Tell your doctor immediately if any of these serious side effects occur: change in amount of urine, skin rash, seizures, joint pain, weight loss, loss of appetite.
- Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach pain, yellowing skin or eyes, dark urine, unusual tiredness, fever, black or bloody stool, red or pink urine, difficulty breathing, change in amount of urine.
- An allergic reaction to Aloprim is unlikely, but stop the allopurinol IV and seek immediate medical attention if it occurs.
- Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
- If you notice any other effects not listed above, contact your doctor or pharmacist.
- Tell your doctor your medical history, especially of: kidney problems, liver problems, gout, any allergies.
- Aloprim may make you drowsy.
- Use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcoholic beverages.
- Caution is advised when using Aloprim in the elderly because they may be more sensitive to the effects of Aloprim.
- Aloprim should be used only when clearly needed during pregnancy.
- Discuss the risks and benefits with your doctor.
- Aloprim passes into breast milk.
- While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
- Tell your doctor of all prescription and nonprescription medication you may use, especially: azathioprine, mercaptopurine, blood thinners (e.g., dicumarol, warfarin), penicillin antibiotics (e.g., ampicillin, amoxicillin), water pills (e.g., furosemide, hydrochlorothiazide), chlorpropamide, cyclosporine, probenecid, sulfinpyrazone, anti-cancer drugs.
- Tell your doctor if you take any drugs that cause drowsiness such as: medicine for sleep, sedatives, tranquilizers, anti- anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines or tricyclics), anti-seizure drugs (e.g., carbamazepine), muscle relaxants, certain antihistamines (e.g., diphenhydramine).
- Check the label on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients.
- Ask your pharmacist about the safe use of these products.
- Do not start or stop any medicine without doctor or pharmacist approval.