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Drug Guide    A   actoplus met

  Prescription drug information   Post your opinion about this drug  

   Actoplus met

Actoplus met
Oral


This combination medication is used along with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes (non-insulin-dependent diabetes). This medication works by helping to restore your body's proper response to the insulin you naturally produce. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (decrease in sexual ability). Pioglitazone belongs to a class of drugs known as thiazolidinediones or "glitazones". Metformin is a biguanide-type drug.

 
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 Actoplus met images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
actoplus met

Uses
This combination medication is used along with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes (non-insulin-dependent diabetes). This medication works by helping to restore your body's proper response to the insulin you naturally produce. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (decrease in sexual ability). Pioglitazone belongs to a class of drugs known as thiazolidinediones or "glitazones". Metformin is a biguanide-type drug.
Notes
  • Do not share this medication with others.It is recommended you attend a diabetes education program to understand diabetes and all the important aspects of its treatment, including meals/diet, exercise, personal hygiene, medications, and getting regular eye, foot and medical exams.Lifestyle changes that help promote healthy bones include increasing weight-bearing exercise, eating well-balanced meals containing adequate calcium and vitamin D, stopping smoking, and limiting alcohol.
  • Consult your doctor to see if you need to take calcium/vitamin D supplements and discuss lifestyle changes that might benefit you.Keep all medical appointments.
  • Laboratory and/or medical tests (e.g., liver and kidney function tests, fasting blood glucose, hemoglobin A1c, complete blood counts) will be performed from time to time to monitor for side effects and response to therapy.
  • Regularly check your blood or urine for sugar as directed by your doctor or pharmacist.

Storage
  • Store at room temperature (77 degrees F or 25 degrees C) away from light and moisture.
  • Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: rapid/difficult breathing, severe drowsiness, slow/irregular heartbeat.

How To Use
  • Take this medication by mouth, usually once or twice daily with a meal or as directed by your doctor.The dosage is based on your medical condition and response to therapy.
  • Taking more than 45 milligrams of pioglitazone per day, or more than 2550 milligrams of metformin per day, is not recommended unless your doctor directs you otherwise.Use this medication regularly in order to get the most benefit from it.
  • To help you remember, use it at the same time(s) each day.

Side Effects
  • Nausea, stomach upset, diarrhea, loss of appetite and metallic taste may occur at the beginning of treatment as your body adjusts to the medication.
  • If stomach symptoms return later (after you are on the same dose for several days or more), tell your doctor immediately.
  • Returning stomach symptoms may be due to lactic acidosis.
  • (See also Warning section)Headache, dizziness, tooth problems, weight gain, stuffy nose, cough and fever may also occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling of the hands/feet (edema), unusual tiredness/weakness, sudden weight gain, trouble breathing, new/worsening vision problems (e.g., color or night vision problems), bone fracture.Seek immediate medical attention if any of these rare but very serious side effects occur: vomiting, stomach pain, yellowing eyes/skin, dark urine.This medication usually does not cause low blood sugar (hypoglycemia), but this effect may occur if you do not consume enough calories (from food, juices, fruit, etc.).
  • The symptoms include chills, cold sweat, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands/feet, or hunger.
  • It is a good habit to carry glucose tablets or gel to treat low blood sugar.
  • If you are in a situation where you don't have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level.
  • Tell your doctor immediately about the reaction.
  • To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals.Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor.
  • If these symptoms occur, tell your doctor immediately.
  • Your medication dosage may need to be increased.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking pioglitazone/metformin, tell your doctor or pharmacist if you are allergic to it; or to other "glitazones" such as rosiglitazone; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: kidney disease, history of liver disease, conditions that may cause a low level of oxygen in the blood or poor circulation (e.g., severe congestive heart failure, recent heart attack, recent stroke), lack of body fluids (dehydration), serious infection, metabolic acidosis (e.g., diabetic ketoacidosis), type 1 diabetes (insulin-dependent diabetes).Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (e.g., obstructive lung disease, severe asthma), other heart problems (e.g., coronary artery disease, history of heart bypass surgery), blood problems (e.g., anemia, vitamin B-12 deficiency), swelling (edema), fertility problems (e.g., ovulation problems), other liver problems, upcoming surgery, alcohol use, eye (retina) problems.You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels; use caution engaging in activities requiring alertness such as driving or using machinery.Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar.During times of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar.
  • Consult your doctor, as a change in your medication or how often you test your blood sugar may be required.This medication may increase the risk of bone fracture (e.g., upper arm, hand, foot, ankle) in female patients.
  • To lower the chance of getting injured, use caution when doing activities such as contact sports.Kidney function declines as you grow older.
  • The metformin in this product is removed by the kidneys.
  • Therefore, elderly people may be at a greater risk for low blood sugar and lactic acidosis while using this drug.Children may be more sensitive to the effects of this drug, especially low blood sugar.This medication can cause changes in the menstrual cycle (promote ovulation) in women with certain fertility problems, increasing the risk of becoming pregnant.
  • Consult your doctor or pharmacist about the use of reliable birth control while using this medication.This medication should be used only when clearly needed during pregnancy.
  • Discuss the risks and benefits with your doctor.
  • Your doctor may substitute insulin for this drug during your pregnancy.
  • Follow all instructions carefully.The metformin in this product passes into breast milk.
  • Breast-feeding is not recommended while using this drug.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
  • Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: birth control pills, bupropion, calcium channel blockers (e.g., nifedipine), cephalexin, cimetidine, corticosteroids (e.g., prednisone), decongestants, other diabetes drugs (e.g., glyburide, acarbose, insulin), estrogens, herbal products (e.g., fenugreek, gymnema, ginseng), isoniazid, niacin, phenothiazines (e.g., chlorpromazine), phenytoin, thyroid drugs, "water pills" (diuretics such as hydrochlorothiazide, furosemide), drugs affecting liver enzymes that remove this medication from your body (e.g., gemfibrozil, rifamycins including rifampin).Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia).
  • Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.If you are scheduled to undergo any X-ray or scanning procedure using injectable iodinated contrast material, be sure to inform your doctor that you are taking this medication.
  • You will need to temporarily stop this medication around the time of your procedure.
  • Consult your doctor for further instructions.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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