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Drug Guide    A   accuretic

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Quinapril/hctz Oral

Quinapril HCl/hydrochlorothiazide is used to treat high blood pressure (hypertension). High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems.

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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions

Quinapril HCl/hydrochlorothiazide is used to treat high blood pressure (hypertension). High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems.

  • Store at room temperature between 68 and 77 degrees F (20 and 25 degrees C) away from light and moisture.

  • If overdose is suspected, contact your local poison control or emergency room immediately.
  • Symptoms of overdose may include severe dizziness, fainting, or mental/mood changes.

Pfizer Argentina - ACCURETIC
Pfizer Argentina - ACCURETIC

How To Use
  • Accuretic is best taken on an empty stomach (one hour before or two hours after a meal), or with a light meal.
  • High-fat meals, however, may decrease the absorption of the medicine into your bloodstream.
  • Take it exactly as prescribed and try to take it at the same time each day.
  • If you are taking a tetracycline antibiotic or a quinolone (e.g., ciprofloxacin, levofloxacin) antibiotic, take it at least 3 hours apart from Accuretic.
  • This product contains magnesium, which can interfere with absorption of these antibiotics.
  • Take Accuretic exactly as prescribed by your doctor.
  • Do not skip doses or stop taking Accuretic unless directed to do so by your doctor.
  • It is important to continue taking Accuretic even if you feel well.
  • Most people with high blood pressure do not feel sick.

Side Effects
  • Nausea, diarrhea, cough, increased urination, headache, and sun sensitivity may occur.
  • If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
  • Tell your doctor immediately if any of these serious side effects occur: dizziness, lightheadedness.
  • Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: difficulty swallowing/ tightness in the throat, decrease in the amount of urine, unusual weakness, muscle pain or cramps, persistent sore throat or fever, unusual bleeding or bruising, chest pain, irregular pulse, seizures, tingling or numbness of the hands or feet.
  • If you notice the following unlikely but serious side effect, stop taking Accuretic and seek immediate medical attention: fainting.
  • Accuretic may rarely cause serious (possibly fatal) liver problems.
  • If you notice any of the following highly unlikely but very serious side effects, seek immediate medical attention: yellowing of the eyes or skin, dark urine, stomach/abdominal pain, persistent fatigue, persistent nausea.
  • An allergic reaction to Accuretic is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
  • If you notice other effects not listed above, contact your doctor or pharmacist.

  • Tell your doctor your medical history especially: kidney/liver/bone marrow/heart problems, autoimmune disease (e.g., systemic lupus erythematosus, scleroderma), high or low blood levels of potassium (hyperkalemia, hypokalemia), high blood levels of calcium (hypercalcemia), stroke (cerebrovascular disease), pancreas problems (pancreatitis), trouble swallowing, diabetes, gout, sodium-restricted diet, high cholesterol, nerve problems (sympathectomy), scheduled medical/dental surgery or anesthesia.
  • Inform your doctor about any drug allergies you may have, especially to: ACE inhibitors (e.g., lisinopril, captopril), hydrochlorothiazide, sulfa drugs (e.g., sulfamethoxazole).
  • Accuretic is not recommended for use if you have the following medical conditions: severe kidney disease (anuria), previous history of swelling of the mouth/face/throat known as "angioedema (especially after the use of ACE inhibitors).
  • Accuretic may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
  • Limit alcoholic beverages and avoid overheating because this may cause dizziness and lightheadedness.
  • To avoid dizziness or lightheadedness when rising from a seated or lying position, get up slowly.
  • Persistent diarrhea, vomiting, and sweating and decreased fluid intake can lead to dehydration and cause dizziness and lightheadedness due to low blood pressure.
  • Contact your doctor if you are unable to drink fluids; have persistent diarrhea or vomiting; or have excessive sweating.
  • Accuretic can increase sensitivity to sunlight.
  • Avoid prolonged exposure to direct and/or artificial light.
  • Wear protective clothing and sunscreen.
  • Accuretic should be used only when clearly needed during the first three months of pregnancy.
  • Accuretic is not recommended for the last six months of pregnancy.
  • Consult your doctor for more details.
  • The quinapril and hydrochlorothiazide in Accuretic pass into breast milk and may have undesirable effects on a nursing infant.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Accuretic is not recommended for use with cisapride, dofetilide.
  • Ask your doctor or pharmacist for more details.
  • Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially of: water pills (e.g., furosemide, spironolactone, triamterene), other drugs used to treat high blood pressure, corticosteroids (e.g., prednisone), NSAIDs (e.g., ibuprofen, naproxen, ketoprofen), certain diabetes medications (e.g., insulin, glyburide, glipizide), barbiturates (e.g., phenobarbital), narcotics (e.g., codeine), muscle relaxants (e.g., tubocurarine), sympathomimetic drugs (e.g., norepinephrine), lithium, ACTH (adrenocorticotropic hormone), tetracycline, cholestyramine, colestipol, digoxin, potassium supplements.
  • Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure.
  • Ask your pharmacist about the safe use of these products.
  • Do not use potassium-containing salt substitutes while taking Accuretic.
  • Consult your doctor or pharmacist for more information.
  • Accuretic can affect the results of certain lab tests (e.g., parathyroid).
  • Make sure laboratory personnel and your doctors know you use Accuretic.
  • Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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