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Drug Guide    A   a-Hydrocort

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Hydrocortisone Sodium Suc.-Inj

Hydrocortisone sodium succinate is a corticosteroid-type hormone used as a supplement when the body is not producing enough of the natural hormone, cortisol. Hydrocortisone sodium succinate is also used to suppress (inhibit) the immune system in order to treat conditions such as allergies, rejection of transplanted organs, or rheumatoid arthritis.


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 A-Hydrocort images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions

Hydrocortisone sodium succinate is a corticosteroid-type hormone used as a supplement when the body is not producing enough of the natural hormone, cortisol. Hydrocortisone sodium succinate is also used to suppress (inhibit) the immune system in order to treat conditions such as allergies, rejection of transplanted organs, or rheumatoid arthritis.

  • Store at room temperature between 68 and 77 degrees F (20 to 25 degrees C) away from light and moisture.
  • After mixing and dilution in correct IV fluids, A-Hydrocort is stable at room temperature for up to 72 hours if protected from light Consult your pharmacist for details.
  • Discard any unused liquid.

  • If overdose is suspected, contact your local poison control center or emergency room immediately.

How To Use
  • Give A-Hydrocort directly into a vein (IV) or into a muscle (IM), as directed by the doctor.
  • The dosage and length of treatment depends on your medical condition and response to therapy.
  • Follow all instructions for proper mixing and dilution with correct IV fluids.
  • If you have questions regarding the use of A-Hydrocort, consult your pharmacist.
  • Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.
  • Use A-Hydrocort exactly as prescribed.
  • Do not increase your dose, take it more frequently, or use it for a longer period of time than prescribed.
  • Also, do not suddenly stop using A-Hydrocort without your doctor s approval.
  • You may be switched to an oral corticosteroid when you are able to take drugs by mouth.

Side Effects
  • Nausea or stomach upset may occur.
  • If either of these effects persist or worsen, notify your doctor promptly.
  • Tell your doctor immediately if any of these serious side effects occur: increased appetite, stomach pain, headache, increased thirst or urination, unusual weight loss or gain, mental/mood changes, trouble sleeping, reddening of the face or neck.
  • Tell your doctor immediately if any of these unlikely but serious side effects occur: vision problems, eye pain, seizures, changes in the appearance of the skin, problems with wounds healing, unusual bruising, unusual weakness, unusual menstrual periods, failure to grow (in children), excess hair growth, tendon or bone/joint pain.
  • An allergic reaction to A-Hydrocort is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
  • If you notice other effects not listed above, contact your doctor or pharmacist.

  • Tell your doctor your medical history, especially of: any allergies (especially to corticosteroids such as prednisone), thyroid conditions (e.g., hyperthyroid, hypothyroid), bone loss (e.g., osteoporosis), stomach problems (e.g., ulcers, ulcerative colitis), heart problems (e.g., congestive heart failure), current infections (e.g., tuberculosis, fungal, parasitic infection), eye problems (e.g., herpes infection, cataracts, glaucoma), nerve problems (e.g., myasthenia gravis), bleeding problems (e.g., hypoprothrombinemia), liver problems, high blood pressure, seizures, diabetes, recent vaccinations, mental/mood problems, kidney problems.
  • A-Hydrocort can lower the body s ability to fight an infection.
  • Notify your doctor promptly if you develop any signs of an infection such as fever, chills, or sore throat.
  • Also, contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or any other new symptoms.
  • Avoid contact with people currently infected with chicken pox or the measles.
  • Consult your doctor immediately if you think you have been exposed to the chicken pox or measles virus.
  • Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received live vaccines (e.g., oral polio vaccine).
  • A-Hydrocort is not recommended for use in premature infants.
  • Caution is advised when prescribing or using A-Hydrocort in children since they may be more sensitive to the effects of A-Hydrocort.
  • A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death) if given by injection to an infant during the first months of life (neonatal period).
  • The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol.
  • Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat.
  • Report these symptoms to the doctor immediately should they occur.
  • If possible, a preservative-free product should be used when treating neonates.
  • Caution is advised when prescribing or using A-Hydrocort in the elderly since they may be more sensitive to the effects of A-Hydrocort.
  • A-Hydrocort should be used only when clearly needed during pregnancy.
  • Discuss the risks and benefits with your doctor.
  • It is not known if A-Hydrocort passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose or the dose is interrupted, contact your doctor or pharmacist immediately to establish a new dosing schedule.

Drug Interactions
  • Tell your doctor of all prescription and nonprescription medication you may use, especially: phenytoin, barbiturates (e.g., phenobarbital, primidone), rifamycin antibiotics (e.g., rifampin, rifabutin), macrolide antibiotics (e.g., clarithromycin, erythromycin), high-dose aspirin or aspirin-like drugs (e.g., salsalate, magnesium salicylate), neuromuscular blocking drugs (e.g., pancuronium, vecuronium), "water pills (e.g., potassium-sparing diuretics such as spironolactone or triamterene), antifungal drugs (e.g., itraconazole, ketoconazole), anticholinesterase drugs (e.g., ambenonium, pyridostigmine), estrogen-containing drugs (e.g., birth control pills, estradiol) or blood thinners (e.g., warfarin).
  • A-Hydrocort can affect the results of certain lab tests.
  • Make sure laboratory personnel and your doctors know you use A-Hydrocort.
  • Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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