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Drug Guide    Z   Zileuton

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   Zileuton

Zileuton
Oral


This medication is used to control long-term (chronic) asthma and help decrease the number of asthma attacks. Controlling asthma can decrease time lost from work or school. This drug improves asthma symptoms by blocking substances in the body called leukotrienes. It will not treat a sudden asthma attack.

 
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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Zileuton

Uses
This medication is used to control long-term (chronic) asthma and help decrease the number of asthma attacks. Controlling asthma can decrease time lost from work or school. This drug improves asthma symptoms by blocking substances in the body called leukotrienes. It will not treat a sudden asthma attack.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., liver function, lung function) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.Avoid allergens, irritants, smoking, and other factors that make asthma worse.

Storage
  • Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.


How To Use
  • Read the Patient Information Leaflet provided by your pharmacist before you start using zileuton and each time you get a refill.
  • If you have any questions, consult your doctor or pharmacist.
  • Take this medication by mouth with or without food, usually 4 times daily or as directed by your doctor.Continue taking this drug as directed, even during sudden asthma attacks.
  • Do not stop taking this medication unless directed to do so by your doctor.
  • Do not take more than the prescribed dose.
  • Also, do not decrease the dose or stop taking any other asthma medication unless directed to do so by your doctor.Use this medication regularly to get the most benefit from it, even during asthma attacks and periods when you have no asthma symptoms.
  • To help you remember, take it at the same times each day.Seek immediate medical attention if your asthma symptoms worsen, if you notice that you are using more of your quick-relief inhaler (e.g., albuterol, salbutamol), or if you need to use the quick-relief inhaler more than the maximum number of times prescribed in 24 hours.

Side Effects
  • Nausea, drowsiness, constipation, dizziness, trouble sleeping, gas, joint pain, eye redness, or vomiting may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, neck pain/stiffness.Seek immediate medical attention if any of these rare but very serious side effects occur: yellowing skin/eyes, dark urine, severe stomach/abdominal pain, unusual tiredness, flu-like symptoms (e.g., headache, fever, chills, muscle aches).A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking zileuton, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: active liver disease.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease.This drug may make you dizzy or drowsy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Limit alcoholic beverages because alcohol may add to this drug's drowsiness/dizziness effects and possible liver problems.Caution is advised when using this drug in elderly women because they may be more sensitive to the effects of the drug, especially liver toxicity.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
  • Therefore, breast-feeding is not recommended while using zileuton.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: propranolol, theophylline, tizanidine, warfarin.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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