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Drug Guide    Z   Ziconotide IT

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   Ziconotide IT

Ziconotide IT



This medication is a non-narcotic pain reliever that is used to treat ongoing pain when other treatments or medications cannot control your pain. Ziconotide works by blocking the nerves in the spinal cord that send pain signals. It decreases ongoing pain caused by cancer, AIDS, failed back surgery, multiple sclerosis, neuropathy, and other causes.

 
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 Ziconotide IT images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Ziconotide IT

Uses
This medication is a non-narcotic pain reliever that is used to treat ongoing pain when other treatments or medications cannot control your pain. Ziconotide works by blocking the nerves in the spinal cord that send pain signals. It decreases ongoing pain caused by cancer, AIDS, failed back surgery, multiple sclerosis, neuropathy, and other causes.
Notes
  • Laboratory and/or medical tests (e.g., CK levels) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.Do not share this medication with others.

Storage
  • Refrigerate between 36-46 degrees F (2-8 degrees C) away from light and moisture at all times, including during transport.
  • After being mixed with saline, it may be refrigerated for up to 24 hours.
  • Do not freeze.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.


How To Use
  • Read the instruction manual and directions that come with your infusion pump.
  • If you have any questions regarding the information, consult your doctor or pharmacist.This medication is injected, usually continuously, into the spinal fluid (intrathecal) using a small pump or as directed by your doctor.
  • To decrease the risk of side effects, treatment is usually started slowly and then gradually increased to the best dose for you.
  • Your dose is based on your condition and response to therapy.This medication should not be given into a vein (IV) or under the skin.
  • It can cause fainting due to a dangerous drop in blood pressure if it is accidentally given into a vein.To prevent infection, learn how to handle the infusion pump, and learn proper care of the injection site.
  • Call your doctor immediately if there is any sign of infection around the injection site (e.g., swelling, redness, tenderness).
  • See also Side Effects section.Contact your doctor or pharmacist to set up a schedule for refilling your pump.Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.Inform your doctor if your pain persists or worsens.

Side Effects
  • Dizziness, drowsiness, nausea, headache, and weakness may occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: decreased alertness (unresponsiveness), confusion, memory problems, mental/mood changes (e.g., anxiety, depression, hallucinations, thoughts of suicide), new or worsening muscle pain/soreness, numbness/tingling, trouble speaking/swallowing, difficult/unsteady walking, trouble urinating, dark urine, vision changes.A very serious infection (meningitis) may occur if the site of your infusion or the solution going into your spinal cord becomes contaminated.
  • Symptoms of meningitis include mental changes (e.g., extreme drowsiness, confusion), high fever, seizures, severe headache, stiff neck, nausea, and vomiting.
  • Seek immediate medical attention if any of these unlikely but very serious side effects occur.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking ziconotide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: uncontrolled bleeding, any infection near the injection site, mental/mood disorders (e.g., depression, psychosis, thoughts of suicide), spinal canal blockage.Before using this medication, tell your doctor or pharmacist your medical history, especially of: regular/long-term use of narcotic medication.This medication is not a narcotic (morphine-like drug).
  • If you have been using a narcotic (e.g., codeine, hydrocodone, morphine) regularly for more than a few weeks, or if it has been used in high doses, you may be dependent on it.
  • In such cases, if you suddenly stop the narcotic, withdrawal reactions may occur.
  • This medication will not prevent withdrawal reactions from narcotics.
  • When stopping extended, regular treatment with narcotics, gradually reducing the dosage as directed will help prevent withdrawal reactions.
  • Consult your doctor or pharmacist for more details.This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery.
  • Avoid alcoholic beverages.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially confusion.This medication should be used only when clearly needed during pregnancy.
  • Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
  • Because of the potential risk to a nursing infant, breast-feeding while using this drug is not recommended.
  • Consult your doctor before breast-feeding.

Missed Dose
  • Not Applicable.

Drug Interactions
  • Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
  • Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: "water pills" (e.g., furosemide, thiazide diuretics).Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients.
  • Ask your pharmacist about the safe use of those products.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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