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Additional Details
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Drug Guide    Z   Zepine

  Prescription drug information   Post your opinion about this drug  

   Zepine

Zepine
Oral


This medication is used to treat mild high blood pressure (hypertension) and with other medications to treat more severe high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Reserpine may rarely be used to treat certain mental/mood disorders (e.g., agitated psychotic states) in those who can not tolerate the usual treatments. Reserpine belongs to a class of drugs known as centrally acting antihypertensives. It works by decreasing the levels of certain brain chemicals (neurotransmitters), thereby slowing the heartbeat, relaxing blood vessels, and decreasing blood pressure.

 
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 Zepine images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Zepine

Uses
This medication is used to treat mild high blood pressure (hypertension) and with other medications to treat more severe high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Reserpine may rarely be used to treat certain mental/mood disorders (e.g., agitated psychotic states) in those who can not tolerate the usual treatments. Reserpine belongs to a class of drugs known as centrally acting antihypertensives. It works by decreasing the levels of certain brain chemicals (neurotransmitters), thereby slowing the heartbeat, relaxing blood vessels, and decreasing blood pressure.
Notes
  • Do not share this medication with others.Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine.
  • Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Keep all medical appointments so that your doctor can monitor your progress or check for side effects.
  • Consult your doctor for more details.Have your blood pressure checked regularly while taking this medication.
  • Learn how to monitor your own blood pressure, and share the readings with your doctor.

Storage
  • Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: severe drowsiness, severe dizziness, flushing, very red eyes, small pupils, feeling cold, low body temperature, unusually slow breathing, very slow heartbeat, fainting.

How To Use
  • Take this medication by mouth, usually 1 to 2 times daily or exactly as prescribed by your doctor.Dosage is based on your medical condition, tolerance of side effects, and response to treatment.
  • Your doctor may direct you to start by taking a lower dose, then increase it gradually (every 10 days) until your blood pressure is lowered.Use this medication and other blood pressure medications regularly to get the most benefit from it.
  • To help you remember, take it at the same time(s) each day.
  • It is important to continue taking this medication even if you feel well.
  • Most people with high blood pressure do not feel sick.
  • It may take up to several weeks before the full benefit of this drug takes effect.Do not stop taking this medication without first consulting your doctor.
  • Some conditions may become worse when the drug is abruptly stopped.
  • Your dose may need to be gradually decreased.Tell your doctor if your condition worsens (e.g., your routine blood pressure readings increase) or you experience severe side effects.

Side Effects
  • Drowsiness, dizziness, stuffy nose, increased saliva, and acid stomach may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication may develop serious side effects, but with frequent visits to your doctor, this risk can be reduced.Tell your doctor immediately if you develop signs of depression (e.g., persistent blue mood, severe sadness, thoughts of suicide, problems sleeping, loss of appetite).
  • Depression may last for some time after stopping the medication.
  • Your doctor may monitor you for worsening of symptoms until depression improves.Tell your doctor immediately if any of these unlikely but serious side effects occur: abdominal pain/cramps, nosebleeds, diarrhea, nausea, vomiting, fainting, chest pain, slow heartbeat, shortness of breath, swelling, enlarged breasts, unusual breast discharge, decreased sexual interest/ability, other mental/mood changes (e.g., nervousness, anxiety, slowed thinking, nightmares) uncomfortable urination, headache, unusual weight gain.Tell your doctor immediately if any of these rare but very serious side effects occur: fast/irregular heartbeat, muscle aches, hearing loss, eye/vision problems (e.g., blurred/decreased vision, red eyes).A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking reserpine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: current or past depression, thoughts of suicide, active stomach ulcer, a certain intestine problem (ulcerative colitis).Reserpine should also not be used if you are currently receiving shock treatments (electroconvulsive therapy-ECT) for a mental/mood condition.Before using this medication, tell your doctor or pharmacist your medical history, especially of: gallbladder problems (gallstones), kidney problems, liver problems.This drug may make you dizzy or drowsy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Avoid alcoholic beverages.Caution is advised when using this drug in the elderly because they may be more sensitive to its drowsiness and depression effects.Before having surgery, tell your doctor or dentist that you are taking this medication.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.This medication passes into breast milk and may have undesirable effects on a nursing infant.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting reserpine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other blood pressure medications (e.g., beta blockers such as propranolol, diuretics such as hydrochlorothiazide, calcium channel blockers such as nifedipine or amlodipine, ACE inhibitors such as lisinopril, among others), digoxin, quinidine, tricyclic antidepressants (e.g., amitriptyline, desipramine), amphetamines (e.g., methylphenidate, mixed amphetamine salts).Before using this medication, tell your doctor or pharmacist if you use any other prescription and nonprescription products that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants (e.g., methocarbamol), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that will last longer if used with this medication (e.g., phenylephrine, pseudoephedrine).
  • Ask your pharmacist about using those products safely.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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