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Drug Guide    W   Wexaphos 4

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   Wexaphos 4

Wexaphos 4
Inj


This medication is used to treat various conditions such as severe allergic reactions, arthritis, blood diseases, breathing problems, certain cancers, eye diseases, intestinal disorders, and skin diseases. It is also used to test for an adrenal gland disorder (Cushing's syndrome). It decreases your body's natural defensive response and reduces symptoms such as swelling and allergic-type reactions. Dexamethasone is a corticosteroid hormone (glucocorticoid). This injectable form of dexamethasone is used when a similar drug cannot be taken by mouth or when a very fast response is needed, especially in patients with severe medical conditions.This drug may also be used with other medications as a replacement for certain hormones.This drug may also be used to prevent nausea and vomiting caused by cancer chemotherapy.

 
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 Wexaphos 4 images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Wexaphos 4

Uses
This medication is used to treat various conditions such as severe allergic reactions, arthritis, blood diseases, breathing problems, certain cancers, eye diseases, intestinal disorders, and skin diseases. It is also used to test for an adrenal gland disorder (Cushing's syndrome). It decreases your body's natural defensive response and reduces symptoms such as swelling and allergic-type reactions. Dexamethasone is a corticosteroid hormone (glucocorticoid). This injectable form of dexamethasone is used when a similar drug cannot be taken by mouth or when a very fast response is needed, especially in patients with severe medical conditions.This drug may also be used with other medications as a replacement for certain hormones.This drug may also be used to prevent nausea and vomiting caused by cancer chemotherapy.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., blood counts, blood glucose/mineral levels, blood pressure, bone density tests, height/weight measurements, eye examinations, X-rays) should be performed periodically to monitor your progress or check for side effects during long-term treatment.
  • Consult your doctor for more details.Lifestyle changes that help reduce the risk of bone loss (osteoporosis) during long-term treatment include doing weight-bearing exercise, getting adequate calcium and vitamin D, stopping smoking, and limiting alcohol.
  • Talk with your doctor about lifestyle changes that might benefit you.If you use this medication for prolonged periods, you should wear or carry identification stating that you are using it.

Storage
  • Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • For single-use vials, discard any unused medication immediately.
  • For the multi-use vials, store at room temperature and discard any unused medication as directed on the package.
  • Keep all medicines away from children and pets.


How To Use
  • This medication is given by injection into a vein , muscle, joint, or skin wound by a health care professional as directed by your doctor.
  • Follow your doctor's directions carefully.
  • Dosage is based on your medical condition and response to treatment.
  • Do not increase your dose or use this drug more often than prescribed without consulting your doctor.
  • Some patients (especially newborns) should receive the preservative-free form of this drug.
  • In these patients, when mixing this form of the drug, be sure to use IV fluid that is also preservative-free.
  • Use these mixtures within 24 hours.
  • Before using this product, check it visually for particles or discoloration.
  • If either is present, do not use the liquid.If this medication is injected into a joint, be careful how much pressure you put on that joint, even if it is feeling better.
  • Ask your doctor how much you can move/use the joint while it is healing.If you have been using this medication for a long time, do not suddenly stop using it without your doctor's approval.
  • Your dose may need to be gradually decreased to reduce symptoms such as weakness, weight loss, nausea, or extreme tiredness.If you are giving yourself injections at home, learn how to prepare and inject this medication properly.
  • Ask your doctor, pharmacist, or nurse any questions you may have about how to give yourself dexamethasone.
  • Learn how to store and discard needles, medical supplies, and any unused medication safely.
  • Never reuse needles or syringes.Tell your doctor if your condition persists or worsens.

Side Effects
  • Stomach upset, headache, dizziness, menstrual period changes, trouble sleeping, increased appetite, weight gain, or pain/redness/swelling at the injection site may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: bone/joint pain, easy bruising/bleeding, black stools, vomit that looks like coffee grounds, severe stomach/abdominal pain, increased thirst/urination, fast/slow/pounding/irregular heartbeat, shortness of breath, swelling of the ankles/feet, tendon pain, persistent weight gain, puffy face, unusual hair growth, thinning skin, slow wound healing, signs of infection (e.g., persistent fever/cough/sore throat, painful urination, eye pain/discharge), muscle weakness/pain, mental/mood changes (e.g., mood swings, depression, agitation), vision changes, seizures, unusual skin growths.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using dexamethasone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., prednisone); or to sulfites; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: current fungal infections.Before using this medication, tell your doctor or pharmacist your medical history, especially of: other infections (e.g., tuberculosis, herpes, cerebral malaria, threadworm), blood clots, brittle bones (osteoporosis), high blood pressure, asthma, heart problems (e.g., congestive heart failure, recent heart attack), diabetes, eye diseases (e.g., cataracts, glaucoma, herpes infection of the eye), kidney disease, severe liver disease (cirrhosis), mental/mood conditions (e.g., psychosis, anxiety, depression), certain nerve/muscle problems (myasthenia gravis), seizures, stomach/intestinal problems (e.g., diverticulitis, ulcer, ulcerative colitis), underactive thyroid gland (hypothyroidism), untreated mineral problems (e.g., low potassium/calcium).This drug may make you dizzy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.This medication may mask signs of infection or put you at greater risk of developing very serious infections.
  • Report to your doctor any injuries or signs of infection (e.g., persistent sore throat/cough/fever, pain during urination, muscle aches) that occur while using this medication or within 12 months after stopping it.If you have been using this medication for a long time, your body may not be able to make enough natural steroids while you are under stress due to infection, surgery, or injury.
  • Your dose may need to be adjusted.
  • If you have stopped using this drug within the past 12 months, you may need to start using it again if your body is under severe stress.
  • Consult your doctor for more details.
  • Tell your doctor immediately if any of these side effects occur: unusual weakness, sudden weight loss, dizziness.Do not have immunizations, vaccinations, or skin tests unless specifically directed by your doctor.
  • Live vaccines may cause serious problems (e.g., infection) if given while you are using this medication.
  • Avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.Avoid contact with people who have chickenpox or measles unless you have previously had these diseases (e.g., in childhood).
  • If you are exposed to one of these infections and you have not previously had it, seek immediate medical attention.If you have a history of ulcers, or if you take large doses of aspirin or other arthritis medication, limit alcoholic beverages while using this medication to decrease the risk of stomach/intestinal bleeding.
  • Consult your doctor or pharmacist for more details.Before having surgery, tell your doctor or dentist that you are using this medication or have used it within the last 12 months.If you have diabetes, this drug may increase your blood sugar levels.
  • Check your blood glucose levels regularly as directed by your doctor.
  • Tell your doctor immediately if you have symptoms such as increased thirst and urination.
  • Your anti-diabetic medication or diet may need to be adjusted.Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially osteoporosis.
  • Talk with your doctor about ways to prevent bone loss.Caution is advised when using this drug for a long time in children.
  • This medication may temporarily slow down a child's rate of growth, but it will probably not affect final adult height.
  • Monitor your child's height periodically.A preservative (benzyl alcohol) that may be found in some dexamethasone products, which are not preservative-free, can infrequently cause serious (sometimes fatal) problems if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life.
  • The risk is also greater with low-birth-weight infants.
  • Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat.
  • If you notice any of these symptoms in your newborn, report them to the doctor immediately.
  • If possible, use the preservative-free form of this drug when treating newborns.This medication should be used only when clearly needed during pregnancy.
  • There have been rare reports of harm to an unborn baby when corticosteroids are used during pregnancy.
  • Discuss the risks and benefits with your doctor.
  • Infants born to mothers who have been using this medication for an extended time may have low levels of corticosteroid hormone.
  • Tell your doctor immediately if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn.This medication may pass into breast milk and could have undesirable effects on a nursing infant.
  • Therefore, breast-feeding is not recommended while using this medication.
  • Consult your doctor before breast- feeding.

Missed Dose
  • If you miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: live vaccines, mifepristone.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting dexamethasone.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: aldesleukin, aminoglutethimide, large doses of aspirin and aspirin-like drugs (salicylates such as salsalate), birth control pills/patch/ring, "blood thinners" (e.g., warfarin), bupropion, caspofungin, cyclosporine, dasatinib, diabetes medications (e.g., glyburide), digoxin, drugs affecting liver enzymes that remove dexamethasone from your body (such as aprepitant, azole antifungals including ketoconazole, barbiturates including phenobarbital, macrolide antibiotics including erythromycin, rifamycins including rifampin, certain anti-seizure medications including phenytoin, carbamazepine), drugs that may cause potassium loss (e.g., amphotericin B, "water pills"/diuretics such as hydrochlorothiazide), ephedrine, estrogen hormone replacement, HIV protease inhibitors (e.g., indinavir), isoniazid, natalizumab, quinolone antibiotics (e.g., levofloxacin), sunitinib, thalidomide.Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that may increase the risk of stomach bleeding from this drug.
  • Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 mg per day).
  • Consult your doctor or pharmacist for more details.This medication may interfere with certain laboratory tests (including skin tests), possibly causing false test results.
  • Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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