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   Sporanox Pulsepak

Sporanox Pulsepak
Oral


Itraconazole is an azole antifungal medication used to treat a variety of fungal infections.This drug may also be used to prevent certain fungal infections in patients with HIV.

 
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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Sporanox Pulsepak

Uses
Itraconazole is an azole antifungal medication used to treat a variety of fungal infections.This drug may also be used to prevent certain fungal infections in patients with HIV.
Notes
  • Do not share this medication with others.This medication has been prescribed for your current condition only.
  • Do not use it later for another infection unless told to do so by your doctor.
  • A different medication may be necessary in that case.Laboratory and/or medical tests (e.g., liver function tests) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.


How To Use
  • Take this medication by mouth with a full meal, usually once or twice daily or as directed by your doctor.The dosage is based on your medical condition and response to therapy.
  • Take this medication exactly as prescribed by your doctor.
  • Some conditions may require you to take this medication for 1 week each month until therapy is completed.This medication works best when the amount of medicine in your body is kept at a constant level.
  • Therefore, take this drug at evenly spaced intervals.
  • If you are taking this medication on a schedule other than every day (e.g., 1 week every month), it may help to mark your calendar with a reminder.You may need to take this medication for several months to treat the infection.
  • Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear.
  • Stopping the medication too early may result in a return of the infection.Take itraconazole 2 hours before or 1 hour after antacids.
  • Antacids may decrease the absorption of this medication.
  • Also, take this medication with a cola drink if you have decreased or no stomach acid (e.g., achlorhydria) or if you take drugs that decrease stomach acid (e.g., H2 blockers such as ranitidine, proton pump inhibitors such as omeprazole).
  • Consult your doctor or pharmacist for more details.The capsule and solution forms of this medication deliver different amounts of medication and may be used for different purposes.
  • Do not switch between the capsule and solution forms without your doctor's permission and directions.Inform your doctor if your condition persists or worsens.

Side Effects
  • See also Warning section.Nausea/vomiting, diarrhea, gas, headache, dizziness, or stomach upset may occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of infection (e.g., fever, persistent sore throat), wheezing, burning/painful/frequent urination, decreased sexual interest/ability, hair loss, muscle cramps/pain, weakness, irregular heartbeat, mental/mood changes (e.g., depression), enlarged breasts in men, ringing in the ears.Tell your doctor immediately if any of these rare but very serious side effects occur: numbness/tingling of the hands/feet.Itraconazole has rarely caused very serious (possibly fatal) liver disease.
  • If you notice any of the following highly unlikely but very serious side effects, stop taking itraconazole and tell your doctor immediately: yellowing eyes/skin, dark urine, persistent nausea/vomiting, stomach/abdominal pain.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing.Itraconazole can commonly cause a mild rash that is usually not serious.
  • However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction.
  • Therefore, seek immediate medical attention if you develop any rash.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • See also Warning section.Before taking itraconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (e.g., ketoconazole); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease (or history of liver disease with other drugs), kidney disease, heart disease (e.g., coronary artery disease, heart valve disease, congestive heart failure), severe lung disease (e.g., chronic obstructive pulmonary disease-COPD), high blood pressure, decreased or no stomach acid (e.g., achlorhydria).This drug may make you dizzy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Avoid alcoholic beverages since they can increase the effects of dizziness and also increase the risk of serious liver problems.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.
  • This medication should not be used to treat fungal nail infections if you are pregnant or could become pregnant during treatment due to the possibility of harm to an unborn baby.
  • Women of childbearing age should start this medication 2 to 3 days after the start of their periods to make sure that they are not pregnant.
  • Consult your doctor for more details and to discuss reliable forms of birth control.
  • It is recommended that men and women using this medication use two effective forms of birth control (e.g., condoms and birth control pills) while taking this medication and for 2 months after stopping it.Itraconazole passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • See also Warning and How to Use sections.Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: alfuzosin, certain benzodiazepines (e.g., oral midazolam, triazolam, alprazolam, estazolam), certain "statin" drugs (e.g., lovastatin, simvastatin), conivaptan, eletriptan, eplerenone, ergot alkaloids (e.g., ergotamine, dihydroergotamine), ivabradine, ranolazine, vardenafil.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting itraconazole.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amiodarone, calcium channel blockers (e.g., verapamil, nifedipine), drugs affecting liver enzymes that remove itraconazole from your body (such as macrolide antibiotics including erythromycin; cimetidine; isoniazid; rifamycins including rifabutin; nevirapine; certain anti-seizure medicines including carbamazepine; phenytoin).This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes.
  • These affected drugs include certain antiarrhythmic medications (e.g., disopyramide, digoxin), certain chemotherapy drugs (e.g., busulfan, docetaxel, vinblastine), certain benzodiazepines (e.g., diazepam, injectable midazolam), certain immunosuppressants (e.g., tacrolimus, cyclosporine, sirolimus), certain "statin" drugs (e.g., atorvastatin), HIV protease inhibitors (e.g., indinavir, ritonavir, saquinavir), certain anti-diabetic drugs (e.g., oral hypoglycemics such as glyburide), halofantrine, alfentanil, fentanyl, solifenacin, buspirone, repaglinide, certain glucocorticosteroids (e.g., dexamethasone, budesonide), certain drugs for male erectile problems (e.g., sildenafil, tadalafil), trimetrexate, aripiprazole, trazodone, tolterodine, "blood thinners" (e.g., warfarin), sunitinib, and cilostazol.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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