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Additional Details
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Drug Guide    S   Slotil

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   Slotil

Slotil
Oral


This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Diphenoxylate is similar to narcotic pain relievers, but it acts mainly to slow the gut. Atropine belongs to a class of drugs known as anticholinergics, which help to dry up body fluids and also slow gut movement.

 
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 Slotil images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Slotil

Uses
This medication is used to treat diarrhea. It helps to decrease the number and frequency of bowel movements. It works by slowing the movement of the intestines. Diphenoxylate is similar to narcotic pain relievers, but it acts mainly to slow the gut. Atropine belongs to a class of drugs known as anticholinergics, which help to dry up body fluids and also slow gut movement.
Notes
  • Do not share this medication with others.
  • It is against the law.

Storage
  • Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Do not freeze the liquid.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: severe drowsiness, muscle weakness, fast heartbeat, high fever, unusually fast/slow/irregular breathing, seizures, loss of consciousness.

How To Use
  • Take this medication by mouth, usually 4 times a day or as directed by your doctor.
  • Dosage is based on your medical condition and response to therapy.
  • In children, dosage is also based on weight.
  • If you need to continue treatment once your diarrhea is controlled, your doctor may direct you to lower your dosage.
  • Do not increase your dose, take it more often, or use it for longer than prescribed.A liquid formulation is available for use in children.
  • Use only the dropper that comes with the bottle to carefully measure out each dose.It is important that you drink the proper amount of fluids and minerals (electrolytes) to prevent loss of body water (dehydration).
  • Tell your doctor immediately if you develop signs of dehydration (e.g., extreme thirst, decreased urination, muscle cramps, weakness, fainting).
  • You may also need to change to a bland diet during this time to reduce irritation to your stomach/intestines.
  • Consult your doctor or pharmacist for more information.This medication may cause dependence, especially if it has been used regularly for an extended time or if it has been used in high doses.
  • In such cases, withdrawal reactions (e.g., stomach cramps, nausea, vomiting) may occur if you suddenly stop this drug.
  • To prevent withdrawal reactions when stopping extended, regular treatment with this drug, gradually reduce the dosage as directed.
  • Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Inform your doctor if your condition does not improve after 2 days.

Side Effects
  • See also Precautions for side effects seen in children.Drowsiness, dizziness, headache, tiredness, blurred vision, dry mouth, and loss of appetite may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: stomach/abdominal pain or swelling, severe nausea, vomiting, mental/mood changes (e.g., confusion, depression), restlessness, numbness/tingling of arms/legs.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking diphenoxylate with atropine, tell your doctor or pharmacist if you are allergic to either drug; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: liver disease (e.g., obstructive jaundice, cirrhosis), diarrhea caused by certain types of infections (pseudomembranous colitis following recent antibiotic therapy, bacterial infection of the gut caused by E.
  • coli, Salmonella, Shigella).Before using this medication, tell your doctor or pharmacist your medical history, especially of: current dehydration or mineral imbalance, a certain type of bowel disease (acute ulcerative colitis).This drug may make you dizzy or drowsy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Limit alcoholic beverages.Liquid forms of this product may contain alcohol.
  • Caution is advised if you have alcohol dependence or liver disease.
  • Ask your doctor or pharmacist about using this product safely.This drug is not recommended for use in children younger than 2 years.
  • Caution is advised when using this drug in children, particularly those with Down's syndrome, because they may be more sensitive to the following side effects: high fever, fast heartbeat, decreased urination, flushing, dry skin/mouth, thirst.
  • Very serious (possibly life-threatening) effects may occur if too much of this medication is taken by children.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.This medication passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: pramlintide.If you are currently using the medication listed above, tell your doctor or pharmacist before starting diphenoxylate with atropine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine), naltrexone.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), barbiturates (e.g., phenobarbital), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients.
  • Ask your pharmacist about using those products safely.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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