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Drug Guide    R   Rebif Titration Pack SubQ

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   Rebif Titration Pack SubQ

Rebif Titration Pack SubQ



This medication is used to treat multiple sclerosis (MS). Interferon is not a cure for MS, but it may help to decrease the number of attacks of increased symptoms such as balance problems/numbness/weakness and slow the worsening of the disease.

 
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 Rebif Titration Pack SubQ images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Rebif Titration Pack SubQ

Uses
This medication is used to treat multiple sclerosis (MS). Interferon is not a cure for MS, but it may help to decrease the number of attacks of increased symptoms such as balance problems/numbness/weakness and slow the worsening of the disease.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., liver function tests, complete blood count, thyroid tests) may be performed to monitor your progress and check for side effects.
  • Consult your doctor for more details.

Storage
  • Store in the refrigerator between 36-46 degrees F (2-8 degrees C) away from light.
  • Do not freeze.
  • Brief storage at or below 77 degrees F (25 degrees C) is permitted for up to 30 days.
  • Do not expose to high temperatures.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.


How To Use
  • Read the Medication Guide provided by your pharmacist before you start using interferon beta 1A and each time you get a refill.
  • Your health care professional will teach you how to use this medication.
  • If you have any questions, consult your doctor or pharmacist.Before injecting each dose, clean the injection site with rubbing alcohol.
  • It is important to change the location of the injection site with each dose to avoid developing problem areas under the skin.
  • Do not inject into skin that is irritated or infected.
  • Inject this medication under the skin in the thigh, abdomen, upper arm, or buttock, usually 3 times a week at least 48 hours apart, or as directed by your doctor.To increase comfort, remove this medication from the refrigerator and let it warm to room temperature for about 30 minutes before injecting.
  • Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.
  • The solution is normally clear or pale yellow.The dosage is based on your medical condition and response to treatment.
  • To reduce your risk of side effects (e.g., flu-like symptoms), your doctor may direct you to start using a low dose and gradually increase your dose over 4 weeks.
  • A starter pack with different doses of medication may be used when starting this medication.
  • Use only the amount of medication your doctor directed you to use (usually half or all of the liquid in the syringe).
  • Follow your doctor's instructions carefully.
  • Use each syringe only once.
  • Discard any unused liquid in the syringe.
  • Do not save for later use.Use this medication at the same time of the day on the same days of the week (e.g., Monday, Wednesday, Friday).
  • To reduce side effects, give the injection in the evening before bedtime.You may need to take other medications to reduce common side effects such as fever and pain (e.g., acetaminophen, ibuprofen).
  • Consult your doctor or pharmacist about how to use these medications safely with interferon.Learn how to store and discard needles and medical supplies safely.
  • Never reuse syringes or needles.
  • Tell your doctor if your condition worsens.

Side Effects
  • Pain/redness/swelling at the injection site and drowsiness may occur.
  • If any of these effects persist or worsen, tell your doctor promptly.Flu-like symptoms such as headache, nausea, fever, chills, tiredness, and muscle aches/pain may occur, especially when you first start this medication.
  • You can reduce these side effects by injecting this medicine at bedtime and using fever reducers/pain relievers such as acetaminophen or ibuprofen.
  • Consult your doctor or pharmacist for more information.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., depression, rare thoughts of suicide), vision changes, gradual change in weight, intolerance to cold or heat, increased urination.Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, persistent sore throat, cough), easy bruising/bleeding, chest pain, fast/irregular heartbeat, sudden increase in weight, swelling hands/legs/feet, seizures, severe stomach/abdominal pain, yellowing eyes/skin, dark urine.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using interferon, tell your doctor or pharmacist if you are allergic to it; or to albumin or latex; or if you have any other allergies.There is a very small risk of getting a virus from this medication because it contains products from human blood.
  • Careful screening of blood donors, special manufacturing methods, and FDA-approved tests are all used to reduce this risk.
  • For more details, talk to your doctor.Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (e.g., anemia, low platelets, low white blood cells), heart disease (e.g., heart failure, irregular heartbeat), liver disease, mental/mood disorders (e.g., depression, psychosis, suicidal thoughts), seizures, thyroid disease, history of alcohol dependence.Limit alcoholic beverages while using this medication.
  • Ask your doctor or pharmacist about how to drink alcohol safely while using this drug.This medication is not recommended for use during pregnancy.
  • It may harm the unborn baby.
  • If you become pregnant or think you may be pregnant, inform your doctor immediately.
  • Consult your doctor for more details.It is not known whether this drug passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, use it as soon as you remember, then skip the next day.
  • Do not use this medication 2 days in a row.
  • Resume your usual schedule the next week.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other drugs that may suppress your immune system (e.g., azathioprine, cyclosporine, prednisone), other drugs/herbals that may harm your liver (e.g., isoniazid, kava, methotrexate, nefazodone), theophylline.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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