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Additional Details
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Drug Guide    P   Pegvisomant SubQ

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   Pegvisomant SubQ

Pegvisomant SubQ



This medication is used for the treatment of acromegaly if you have not had an adequate response to other treatments (e.g., surgery, radiation). Pegvisomant belongs to a class of medications known as growth hormone receptor antagonists. This medicine is a protein designed to reduce the action of human growth hormone (HGH). HGH increases the production of additional chemicals (e.g., IGF-1) in the body that are thought to cause the symptoms associated with acromegaly. Pegvisomant helps decrease the blood levels of IGF-1 and other related proteins.

 
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 Pegvisomant SubQ images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Pegvisomant SubQ

Uses
This medication is used for the treatment of acromegaly if you have not had an adequate response to other treatments (e.g., surgery, radiation). Pegvisomant belongs to a class of medications known as growth hormone receptor antagonists. This medicine is a protein designed to reduce the action of human growth hormone (HGH). HGH increases the production of additional chemicals (e.g., IGF-1) in the body that are thought to cause the symptoms associated with acromegaly. Pegvisomant helps decrease the blood levels of IGF-1 and other related proteins.
Notes
  • Laboratory and/or medical tests (e.g., liver function tests, IGF-1 levels) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.Do not share this medication with others.

Storage
  • Store unmixed drug in the refrigerator between 36 and 46 degrees F (2-8 degrees C).
  • Do not freeze.
  • Inject mixed bag immediately.
  • If you are unable to use right away, the mixed drug may be kept at room temperature but should be used within 6 hours.
  • After use, discard any unused portion left in the vial.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include an increase in symptoms of fatigue.

How To Use
  • Read the manufacturer's patient instructions provided in the package for information on how to properly prepare and inject this medicine.
  • If any of this information is unclear, consult your doctor or pharmacist.Do not shake the vial when preparing the medication; gently roll it back and forth in your palms to dissolve the powder.Before injecting this medication, visually inspect it for any particles or discoloration.
  • The liquid should be clear after mixing.
  • If the liquid is cloudy, discolored, or has any particles in it, do not use it.The first dose is usually given in the doctor's office.
  • You will be instructed by a healthcare professional how to give your injections at home after this.
  • Be sure to ask any questions that you may have regarding pegvisomant use.Inject this medication under the skin (subcutaneously) usually once daily into the upper arm, upper thigh, stomach area, or buttock as directed by your doctor.
  • The maximum regular daily dose should not exceed 30 milligrams.
  • Use this medication regularly in order to get the most benefit from it.
  • To help you remember, use it at the same time(s) each day.Inject the medication into a different area each time.
  • Choose areas that are not bruised, lumpy, or irritated in any way.Learn how to store and discard needles and medical supplies safely.

Side Effects
  • Pain/redness/itching at the injection site, diarrhea, or nausea may occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of the following serious side effects occur: signs of injection site infection (e.g., oozing, warmth, or persistent pain and redness), flu-like symptoms (e.g., chills, fever, muscle aches, weakness), swelling of the hands/feet/ankles, persistent headache, chest pain.Tell your doctor immediately if any of these unlikely but very serious side effects occur: stomach pain, yellowing of eyes and skin, dark urine, fever, unusual fatigue.An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using this medication, tell your doctor or pharmacist your medical history, especially of: tumors/growths, diabetes, liver disease, regular or excessive alcohol use, any allergies (including latex).Pegvisomant should be used only when clearly needed during pregnancy.
  • Discuss the risks and benefits with your doctor.It is not known if this medication passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: Narcotic pain medicines (opioids such as codeine, hydrocodone, morphine), Insulin and any other diabetes medications.This medication may interfere with certain lab test results (e.g., GH levels).
  • Make sure laboratory personnel and your doctors know that you use this medication.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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