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Drug Guide    P   Peg-Intron SubQ

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   Peg-Intron SubQ

Peg-Intron SubQ



Peginterferon alfa-2b is used alone or in combination with ribavirin to treat chronic hepatitis C, a viral infection of the liver.This medication reduces the amount of hepatitis C virus in the body and helps the body's immune system fight the infection. It is not known if peginterferon can cure hepatitis C virus infections (permanently eliminate the virus from your body). It is also not known if this drug can prevent you from passing the virus to others. Practice "safe sex" (including the use of latex condoms) to lower the risk of passing the virus to others.

 
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 Peg-Intron SubQ images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Peg-Intron SubQ

Uses
Peginterferon alfa-2b is used alone or in combination with ribavirin to treat chronic hepatitis C, a viral infection of the liver.This medication reduces the amount of hepatitis C virus in the body and helps the body's immune system fight the infection. It is not known if peginterferon can cure hepatitis C virus infections (permanently eliminate the virus from your body). It is also not known if this drug can prevent you from passing the virus to others. Practice "safe sex" (including the use of latex condoms) to lower the risk of passing the virus to others.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., blood tests, thyroid tests, virus levels, kidney function tests, triglyceride levels) should be performed periodically to monitor your progress.
  • Depending on your medical history, other tests (e.g., EKG) may be needed.
  • Consult your doctor for more details.You may need an eye exam before using this medication.
  • If you have an eye disease or have a condition that places you at greater risk for eye disease (e.g., diabetes), you should then have periodic eye exams while using this drug.Do not change brands of interferon without checking with your doctor or pharmacist.
  • Other interferons may not have the same effects on your disease.

Storage
  • If you are using the dry powder vials: before mixing, store the powder at room temperature (77 degrees F or 25 degrees C) and avoid exposure to heat, light, and moisture.
  • Brief storage from 59-86 degrees F (15-30 degrees C) is permitted.
  • Once mixed, the solution should be used immediately, but may be stored in the refrigerator (36-46 degrees F or 2-8 degrees C) for up to 24 hours.
  • Do not freeze.If you are using a prefilled syringe: before using, store in the refrigerator.
  • To prepare the drug in the syringe, mix the separate powder and liquid in the prefilled syringe by pressing the two halves of the syringe together until you hear a click.
  • After gently mixing, the solution should be used immediately, but may be stored in the refrigerator for up to 24 hours.
  • Do not freeze.Each vial or prefilled syringe can be used only once; discard any unused portion.
  • Keep this medication and any discarded syringes/needles away from children and pets.


How To Use
  • Read and learn all preparation and usage instructions in the Medication Guide provided by your pharmacist before you start using peginterferon alfa 2B and each time you get a refill.
  • If you have any questions regarding the information, consult your doctor or pharmacist.Inject this medication under the skin (subcutaneously) on your thigh, the outer surface of your upper arm, or stomach once weekly or as directed by your doctor.
  • Do not inject near the belly button or at the waistline.
  • Use a different place each time you give yourself an injection.
  • The dose should be given at about the same time on the same day each week.
  • The dosage is based on your body weight, medical condition and response to therapy.Drink plenty of fluids while you are taking this medication, unless your doctor directs you otherwise.
  • Additional administration guidelines may be available in the Medication Guide.Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.
  • Do not shake this medication.
  • Doing so may decrease the effectiveness of this medication.Learn how to store and discard needles and medical supplies safely.

Side Effects
  • Flu-like symptoms (e.g., fever, chills, muscle aches, fatigue, headache, joint pain, nausea, stomach pain) may occur.
  • If instructed to do so, taking pain/fever-reducing medications (e.g., acetaminophen, ibuprofen) or injecting this medication at bedtime may help reduce some of these symptoms.
  • Dry mouth, increased sweating, loss of appetite, weight loss, trouble sleeping, diarrhea, dry skin, redness/swelling at the injection site, throat/sinus infections, or menstrual period problems may also occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Temporary hair loss may occur.
  • Normal hair growth should return after treatment has ended.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: persistent sore throat or fever, easy or unusual bleeding/bruising, unusually severe fatigue, increased thirst/urination.Tell your doctor immediately if any of these rare but very serious side effects occur: chest pain, unusually slow/fast/pounding heartbeat, vision changes, seizures, one-sided weakness, severe stomach pain with nausea/vomiting, bloody diarrhea.This drug may infrequently cause severe mental/mood changes (e.g., suicidal thoughts or severe depression).
  • If you notice these symptoms, stop your treatment with peginterferon and seek immediate medical attention.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using peginterferon alfa-2b, tell your doctor or pharmacist if you are allergic to it; or to polyethylene glycol (PEG); or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: other severe liver disease (e.g., autoimmune hepatitis, hepatic decompensation).Before using this medication tell your doctor or pharmacist your medical history, especially of: psychiatric conditions (e.g., depression), history of drug/alcohol abuse, sleep problems, low blood counts (e.g., red cells, white cells, or platelets), heart disease, thyroid problems, autoimmune disease (e.g., rheumatoid arthritis, lupus, psoriasis), eye problems, kidney disease, lung disease (e.g., COPD, asthma, pneumonia), cancer, inflammation of the bowels (e.g., colitis), pancreatitis, diabetes, other infections (HIV, hepatitis B), high blood triglyceride levels, history of organ transplant.Do not have immunizations/vaccinations without the consent of your doctor.Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.This drug may make you drowsy or dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.This medicine may cause stomach bleeding.
  • Daily use of alcohol and this medicine may increase your risk for stomach bleeding.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects.This medication is not recommended for use during pregnancy because of possible serious harm to the unborn baby.
  • Consult your doctor for more details and to discuss reliable forms of birth control.
  • It is recommended that men and women using this medication use birth control measures while being treated with this medication and for the 6 months after treatment has stopped.
  • If you become pregnant or think you may be pregnant, inform your doctor immediately.It is not known whether this drug passes into breast milk.
  • Because of the potential risk to the infant, breast-feeding while using this drug is not recommended.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take the missed dose as soon as possible during the same day or the next day, then continue on your regular dosing schedule.
  • If several days go by after you miss a dose, contact your doctor or pharmacist to establish a new dosing schedule.

Drug Interactions
  • Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
  • Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use especially of.
  • methadone, theophylline, zidovudine.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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