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Additional Details
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Drug Guide    O   Ofloxacin

  Prescription drug information   Post your opinion about this drug  

   Ofloxacin

Ofloxacin
Oral


This medication is used to treat a variety of bacterial infections. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

 
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 Ofloxacin images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Ofloxacin

Uses
This medication is used to treat a variety of bacterial infections. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
Notes
  • Do not share this medication with others.This medication has been prescribed for your current condition only.
  • Do not use it later for another infection unless told to do so by your doctor.
  • A different medication may be necessary in that case.Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store at room temperature at 77 degrees F (25 degrees C) in a tightly closed container away from light and moisture.
  • Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: severe dizziness.

How To Use
  • Take this medication by mouth with or without food, usually twice a day (in the morning and evening), or as directed by your doctor.Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.The dosage and length of treatment is based on your medical condition and response to treatment.Take this medication 2 hours before or 2 hours after taking any medications containing magnesium, aluminum, or calcium.
  • Some examples include quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), vitamins/minerals, and antacids.
  • Sucralfate, bismuth subsalicylate, iron, and zinc are also included.
  • These medications bind with ofloxacin preventing its full absorption.
  • It is not known whether milk or dairy products prevent absorption of ofloxacin.
  • However, as a precaution, do not eat or drink dairy products within 2 hours before or after taking ofloxacin.Antibiotics work best when the amount of medicine in your body is kept at a constant level.
  • Therefore, take this drug at evenly spaced intervals.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days.
  • Stopping the medication too early may result in a return of the infection.Inform your doctor if your condition persists or worsens.

Side Effects
  • Upset stomach, nausea, diarrhea, headache, dizziness, lightheadedness, or trouble sleeping may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: sunburn-like skin reaction (sun sensitivity), shaking, mental/mood changes (e.g., nervousness, confusion, hallucinations, rare thoughts of suicide).Tell your doctor immediately if any of these rare but very serious side effects occur: severe/persistent headache, vision problems, fast/slow/irregular heartbeat, fainting, hearing changes, unsteadiness, seizures, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, dark urine, unusual tiredness, easy bruising/bleeding, signs of a new infection (e.g., fever, persistent sore throat), unusual change in the amount of urine.Ofloxacin may rarely cause serious nerve problems that may be reversible if identified and treated early.
  • Seek immediate medical attention if you develop any of the following symptoms: pain/numbness/burning/tingling/weakness in any part of the body, changes in how you sense touch/pain/temperature/body position/vibration.This medication may rarely cause tendon damage (e.g., tendonitis, tendon rupture) during or after treatment.
  • Stop exercising, rest, and seek immediate medical attention if you develop joint/muscle/tendon pain or swelling.This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a type of resistant bacteria.
  • This condition may occur during treatment or weeks after treatment has stopped.
  • Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse.
  • Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection.
  • Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing, chest pain.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking ofloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolone antibiotics (e.g., ciprofloxacin, levofloxacin); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizure disorder, conditions that increase your risk of seizures (e.g., brain/head injury, brain tumors), nervous system disorders (e.g., peripheral neuropathy), kidney disease, liver disease, joint/tendon problems (e.g., tendonitis, bursitis), abnormal heart rhythms (e.g., long QT interval, bradycardia), untreated mineral imbalance (e.g., low potassium blood level).If you have diabetes, you may experience changes in blood glucose levels due to infection or use of ofloxacin.
  • Symptoms of high blood sugar include increased thirst and urination.
  • Symptoms of low blood sugar include nervousness, shaking, sweating, fast heartbeat, or hunger.
  • Follow your doctor's instructions to treat your low blood sugar level (e.g., take glucose tablets or gel; eat a quick source of sugar such as table sugar, honey, or candy; drink a glass of orange juice or non-diet soda).
  • Tell your doctor immediately if you experience symptoms of high or low blood sugar while taking this medication.
  • Monitor your blood glucose levels as directed by your doctor.This drug may make you dizzy or lightheaded.
  • Use caution while driving, using machinery, or taking part in any activity that requires alertness.
  • Limit alcoholic beverages.This medication may make you more sensitive to the sun.
  • Avoid prolonged sun exposure, tanning booths, and sunlamps.
  • Use a sunscreen and wear protective clothing when outdoors.Caution is advised when using this medication in children younger than 18 years of age because they may be at greater risk for joint/tendon problems.
  • Discuss the risks and benefits with the doctor.Kidney function declines as you grow older.
  • This medication is removed by the kidneys.
  • Therefore, the elderly may be at greater risk for tendon problems while using this drug, especially if they are also taking corticosteroids (e.g., prednisone, hydrocortisone).
  • The elderly may also be more sensitive to the side effect of ofloxacin on the heart rhythm (QTc prolongation).During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.This medication passes into breast milk.
  • Though there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • See also How to Use section.Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medication because very serious interactions may occur: strontium ranelate.If you are currently using the medication listed above, tell your doctor or pharmacist before starting ofloxacin.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: corticosteroids (e.g., dexamethasone, prednisone), duloxetine, drugs to treat diabetes (e.g., glyburide, insulin), live bacterial vaccines, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), probenecid, theophylline, warfarin.Other drugs besides ofloxacin that may affect the heart rhythm (QTc prolongation in the EKG) include dofetilide, pimozide, procainamide, amiodarone, quinidine, sotalol, and erythromycin, among others.
  • QTc prolongation can infrequently result in serious (rarely fatal) irregular heartbeat.
  • Consult your doctor or pharmacist for more details and for instructions on how you may reduce your risk of this effect.Also report the use of drugs which might increase seizure risk when combined with ofloxacin such as isoniazid (INH), phenothiazines (e.g., thioridazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline), among others.
  • Consult your doctor or pharmacist for details.This medication may interfere with certain laboratory tests (e.g., urine screening for opiates), possibly causing false test results.
  • Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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