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Drug Guide    O   Octamide Pfs

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   Octamide Pfs

Octamide Pfs
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This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used in diabetic patients who have trouble emptying their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide injection is also used to help prevent nausea/vomiting from cancer medications and after surgery. It may also be used with other medications to help empty the stomach of a certain medication taken by mouth (barium) used in taking X-rays of the stomach/intestines.This drug may also be used to treat other conditions such as migraine headache pain, persistent hiccups, and severe nausea/vomiting that can occur with migraine headaches or cancer radiation treatments.

 
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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Octamide Pfs

Uses
This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used in diabetic patients who have trouble emptying their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide injection is also used to help prevent nausea/vomiting from cancer medications and after surgery. It may also be used with other medications to help empty the stomach of a certain medication taken by mouth (barium) used in taking X-rays of the stomach/intestines.This drug may also be used to treat other conditions such as migraine headache pain, persistent hiccups, and severe nausea/vomiting that can occur with migraine headaches or cancer radiation treatments.
Notes
  • Do not share this medication with others.

Storage
  • Store vials at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
  • The mixed drug may be stored at room temperature unprotected from light for up to 24 hours.
  • Keep all medicines away from children and pets.


How To Use
  • This medication is usually given in the hospital by a health care professional into a muscle or vein.
  • It may be given either as a single injection or every 2 to 8 hours, or exactly as prescribed by your doctor.
  • If given into a vein, it must be given slowly over 1 to 2 minutes, or longer for higher doses.
  • Learn the proper way to mix and give this medication according to the manufacturer's instructions.
  • If mixed, this medication should be diluted only in sodium chloride for injection (normal saline).
  • Before giving this medication, inspect it visually for particles or discoloration.
  • If either is present, do not use the liquid.Dosage and length of treatment is based on your medical condition and response to treatment.This medication is given regularly to get the most benefit from it.Immediately tell your doctor if your condition persists or worsens while receiving this medication.

Side Effects
  • Drowsiness, headache, and tiredness may occur.
  • Less common side effects include problems sleeping, dry mouth, constipation, dizziness, and diarrhea.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., confusion, depression, thoughts of suicide, hallucinations, anxiety, agitation), decreased sexual ability, feelings of restlessness/agitation/jitteriness, mask-like facial expression, shuffling walk, drooling, weakness, trouble swallowing, uncontrollable movements of the mouth/face/hands, unusual nipple discharge, enlarged/tender breasts, unusual fluid retention (swelling), changes in menstruation, vision changes, slow or fast irregular heartbeat, fainting, increase in urination, inability to hold urine (incontinence).Tell your doctor immediately if any of these rare but very serious side effects occur: signs of serious infection (e.g., high fever, persistent sore throat, severe chills), signs of liver problems (e.g., persistent nausea/vomiting, severe tiredness, yellowing eyes/skin, dark urine, severe stomach/abdominal pain).This drug may infrequently cause a serious (sometimes fatal) nervous system problem (neuroleptic malignant syndrome).
  • Seek immediate medical attention if you notice any of the following rare but very serious side effects: fever, rigid muscles, increased sweating, fast heartbeat, mental/mood changes, change in the amount of urine.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.These reactions are more common if you have asthma.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using metoclopramide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: bleeding/blockage/hole in the intestines/stomach, pheochromocytoma, seizures, porphyria.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, heart rhythm problems, Parkinson's disease, severe liver problems (e.g., cirrhosis), chronic heart failure, a certain blood enzyme problem (NADH-cytochrome b5 reductase deficiency), diabetes.This drug may make you dizzy or drowsy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Limit alcoholic beverages.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially drowsiness, confusion, mask-like facial expression, shuffling walk, drooling, muscle spasm/weakness, trouble swallowing, and uncontrollable movements of the mouth/face/hands.Caution is advised when using this drug in children because they may be more sensitive to the effects of the drug, especially drowsiness, confusion, mask-like facial expression, shuffling walk, drooling, muscle spasm/weakness, trouble swallowing, and uncontrollable movements of the mouth/face/hands.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.This drug passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, tell your doctor/nurse immediately.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: pramlintide, cabergoline, pergolide.Some medications may block the actions of metoclopramide.
  • Tell your doctor or pharmacist if you are also taking anticholinergic drugs (e.g., antihistamines such as diphenhydramine, benztropine, scopolamine, among others).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting metoclopramide.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: succinylcholine, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).Before using this medication, tell your doctor or pharmacist if you use any other prescription and nonprescription products that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants (e.g., methocarbamol), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).Since metoclopramide increases stomach emptying, drugs that are absorbed from the stomach may not be absorbed as well (e.g., digoxin).
  • Drugs absorbed from the intestines may have increased absorption (e.g., acetaminophen, levodopa, cyclosporine, alcohol, tetracycline).

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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