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Drug Guide    N   Nafarelin Nasl

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   Nafarelin Nasl

Nafarelin Nasl



Nafarelin is used in women to treat a condition in which the tissue that normally lines the inside of the uterus grows in the wrong place (endometriosis). This medication helps to decrease the abnormal tissue and also the symptoms of endometriosis (e.g., pelvic pain, painful menstrual cramps, and pain during/after sex).This medication is also used in children to treat a certain type of early puberty (central precocious puberty, gonadotropin-dependent). It helps to slow the bone aging and height growth rate so that it is near normal and to stop or reverse signs of early puberty (e.g., breast growth in girls, growth of sexual organs in boys).Nafarelin is a man-made hormone that is similar to a natural hormone made by the body (gonadotropin-releasing hormone-GnRH). It works by decreasing the testosterone hormones in boys and estrogen hormones in women and girls.

 
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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Nafarelin Nasl

Uses
Nafarelin is used in women to treat a condition in which the tissue that normally lines the inside of the uterus grows in the wrong place (endometriosis). This medication helps to decrease the abnormal tissue and also the symptoms of endometriosis (e.g., pelvic pain, painful menstrual cramps, and pain during/after sex).This medication is also used in children to treat a certain type of early puberty (central precocious puberty, gonadotropin-dependent). It helps to slow the bone aging and height growth rate so that it is near normal and to stop or reverse signs of early puberty (e.g., breast growth in girls, growth of sexual organs in boys).Nafarelin is a man-made hormone that is similar to a natural hormone made by the body (gonadotropin-releasing hormone-GnRH). It works by decreasing the testosterone hormones in boys and estrogen hormones in women and girls.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., growth/bone age velocity in children) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store the bottle upright at room temperature at 77 degrees F (25 degrees C) away from light.
  • Do not store at temperatures above 86 degrees F (30 degrees C).
  • Do not freeze.
  • Keep all medicines away from children and pets.


How To Use
  • Read the Patient Information Leaflet, which contains instructions for proper use of this medication.
  • Learn all preparation and usage instructions.
  • Consult your doctor or pharmacist if you have any questions.Follow the instructions on how to properly prime the bottle if you are using it for the first time.Gently blow your nose before using this drug.
  • For very young children, it may be necessary to clear the nose with a bulb syringe.Use this medication usually twice daily (about every 12 hours) as directed by your doctor.
  • If you are using more than 1 spray at a time, wait 30 seconds between each spray.
  • Avoid spraying this medication in your eyes.
  • Also, avoid sneezing during or immediately after using this medication because this may decrease the amount of medication absorbed.
  • Follow the detailed instructions for using the spray and cleaning the spray tip.
  • It is important to clean the spray tip after each use.Dosage is based on your medical condition and response to therapy.
  • The length of therapy for women taking this medication for endometriosis is 6 months unless otherwise directed by your doctor.
  • The length of therapy for children taking this medication for early puberty depends on when the doctor decides it is appropriate for puberty to resume.Use this medication regularly to get the most benefit from it.
  • It is important not to miss any doses of this medication, or else this medication may not be effective.
  • To help you remember, use it at the same times each day.Consult your doctor or pharmacist to find out how long each bottle of the nasal spray should last.
  • Do not use the nasal spray bottle longer, even though there might be some medication left over, because this may result in getting too low a dose.
  • Make sure to get your medication refills a few days early so that you will not run out of your medication.Do not increase your dose or take this medication more often than prescribed.
  • Your condition will not improve any faster, and the risk of serious side effects may be increased.
  • Also, do not stop this medication without your doctor's approval.If you need to use a nasal decongestant spray while using this medication, wait at least 2 hours after using this medication before using the decongestant.When you first start this medication, worsening of symptoms may occur (e.g., increased vaginal bleeding in endometriosis, or vaginal bleeding/period, increase in breast size/pubic hair, oily skin, or body odor in early puberty).
  • Such symptoms should get better after the first month of treatment.
  • Inform your doctor if your symptoms worsen or persist after 2 months.

Side Effects
  • Nasal irritation, hot flashes, vaginal discharge, or mood swings may occur in children.
  • Nasal irritation, hot flashes, headaches, mood swings, decreased sexual interest, muscle pain, vaginal dryness, acne, or decrease in breast size may occur in women.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.For women taking this medication, tell your doctor immediately if any of these unlikely but serious side effects occur: abdominal/lower back pain, bone pain, depression.For women taking this medication, tell your doctor immediately if any of these rare but very serious side effects occur: fast/pounding heartbeat, numbness/tingling of arms/legs, eye pain.Rarely, a very serious problem with your pituitary gland (pituitary apoplexy) may occur, usually in the first hour to 2 weeks after your first dose of this medication.
  • Seek immediate medical attention if any of these very serious side effects occur: sudden severe headache, mental/mood changes (e.g., confusion), vision changes, vomiting.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using nafarelin, tell your doctor or pharmacist if you are allergic to it; or to GnRH or other GnRH-like hormones (e.g., leuprolide); or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: unexplained abnormal vaginal bleeding.Before using this medication, tell your doctor or pharmacist your medical history, especially of: smoking, daily alcohol use, bone loss (osteoporosis) or family history of osteoporosis, polycystic ovarian disease, high cholesterol/triglyceride levels.This medication must not be used during pregnancy.
  • It may harm an unborn baby.
  • Consult your doctor for more details and to discuss reliable forms of birth control.
  • Women should start this medication between days 2 and 4 of their period.
  • Although periods and the release of eggs (ovulation) may stop while you are taking this drug, this should not be considered a reliable form of birth control.
  • It is recommended that men and women using this medication use two effective non-hormonal forms of birth control (e.g., condoms and diaphragm with spermicide) while taking this medication.
  • Consult your doctor.It is not known if this medication passes into breast milk.
  • Because of the potential risk to the infant, breast-feeding is not recommended while using this drug.
  • Consult your doctor before breast-feeding.

Missed Dose
  • It is important that you do not miss any doses of this medication.
  • If you do miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.Vaginal bleeding may occur in girls/women who miss doses of this medication.

Drug Interactions
  • See also How to Use section.Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: estrogens, birth control pills, medications that can cause bone loss (e.g., corticosteroids such as prednisone).This medication may interfere with certain laboratory tests (including tests for pituitary gonadotropic and gonadal functions), possibly causing false test results.
  • Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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