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Drug Guide    I   Interferon Gamma-1B SubQ

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   Interferon Gamma-1B SubQ

Interferon Gamma-1B SubQ



This medication is used to reduce the frequency and severity of serious infections due to chronic granulomatous disease, a disorder that runs in families. This drug is often used along with antibiotics to help prevent these serious infections.This medication is also used to slow the worsening of malignant osteopetrosis, another disorder that runs in families, that affects bones, nerves, and blood.This medication is the same as a protein that your body naturally produces (interferon). In the body, it is thought to work by affecting cell function/growth and the body's natural defenses (immune system) in many ways. Adding more interferon may help your body fight off serious infections.

 
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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Interferon Gamma-1B SubQ

Uses
This medication is used to reduce the frequency and severity of serious infections due to chronic granulomatous disease, a disorder that runs in families. This drug is often used along with antibiotics to help prevent these serious infections.This medication is also used to slow the worsening of malignant osteopetrosis, another disorder that runs in families, that affects bones, nerves, and blood.This medication is the same as a protein that your body naturally produces (interferon). In the body, it is thought to work by affecting cell function/growth and the body's natural defenses (immune system) in many ways. Adding more interferon may help your body fight off serious infections.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., complete blood count, kidney and liver function tests) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store in the refrigerator between 36-46 degrees F (2-8 degrees C) away from light and moisture.
  • Do not freeze.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.Do not leave vials out of the refrigerator for longer than 12 hours.
  • Discard any unused portion of the vial or any vials left out of the refrigerator for longer than 12 hours.


How To Use
  • Read the Patient Information Leaflet available from your pharmacist before you start using this medication and each time you get a refill.
  • Learn all preparation and usage instructions given by the manufacturer.
  • If you have any questions, consult your doctor or pharmacist.Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.
  • Do not shake the vial.
  • Doing so may decrease the effectiveness of the drug.Inject this medication under the skin, usually 3 times weekly (e.g., Monday, Wednesday, and Friday) or as directed by your doctor.
  • This medication is best used in the evening before bedtime to reduce side effects.It is important to change the location of the injection site with each dose to avoid problem areas under the skin.
  • Therefore, choose a different injection site with each dose.
  • The thighs and upper arms are recommended sites for the injection.
  • Do not inject into skin that is irritated, sore, or infected.Dosage is based on your medical condition and response to therapy.
  • Do not change the dose or how often you use this medication without your doctor's approval.
  • Use this medication regularly to get the most benefit from it.
  • To help you remember, use it at the same time each evening that you have a scheduled dose.Learn how to store and discard needles and medical supplies safely.
  • Never reuse syringes or needles.
  • Consult your pharmacist for details.

Side Effects
  • Injection site reactions (pain/swelling/redness), diarrhea, upset stomach, nausea, or vomiting may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Flu-like symptoms such as headache, tiredness, fever, chills, and muscle aches may occur, especially when you first start this medication.
  • These symptoms usually last about 1 day after the injection and improve or go away after a few months of continued use.
  • You can reduce these side effects by injecting this medicine at bedtime and using a fever reducer/pain reliever such as acetaminophen before or after each dose.
  • Consult your doctor or pharmacist for more information.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: lightheadedness, fainting, mental/mood changes (e.g., confusion, depression), shaking (tremors), trouble walking, slow/fast/irregular heartbeat, shortness of breath, swelling of the ankles/feet, increasing tiredness, joint pain, butterfly-shaped rash on the face.Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, persistent nausea/vomiting, seizures, signs of infection (e.g., fever, persistent sore throat), stomach/abdominal pain, black/tarry stools, dark urine, change in the amount of urine, yellowing eyes/skin.Seek immediate medical attention if any of these rare but very serious side effects occur: chest/jaw/left arm pain, weakness on one side of the body, slurred speech, sudden vision changes, pain/redness/swelling of the arms/legs, calf pain/swelling that is warm to the touch, coughing up blood.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking interferon, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., angina, irregular heartbeat, congestive heart failure), liver disease, seizure disorder, blood cell disorders (e.g., anemia, neutropenia, thrombocytopenia).Children, especially those younger than 1 year, may be at greater risk for effects on the liver while using this drug.
  • The manufacturer recommends regular laboratory tests (liver function tests), especially in children younger than 1 year.This medication is not recommended for use during pregnancy.
  • Consult your doctor for more details.It is not known whether this drug passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, use it as soon as you remember.
  • Contact your doctor to establish a new dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs that may affect your immune system (e.g., cancer chemotherapy, prednisone, cyclosporine), hydroxyurea, theophyllines (e.g., aminophylline, theophylline).

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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