Ifosfamide is used to treat various cancers (e.g., testicular cancer, sarcomas, lung cancer). It works by slowing or stopping the growth of cancer cells.
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Overview | Photos | How
To Use | Side
Effects | Precautions | Missed
Dose | Drug
Interactions | |
Ifosfamide
Uses
Ifosfamide is used to treat various cancers (e.g., testicular cancer, sarcomas, lung cancer). It works by slowing or stopping the growth of cancer cells. Notes
- Laboratory and/or medical tests (e.g., complete blood counts, blood salt/mineral levels, kidney function tests) should be performed periodically to monitor your progress or check for side effects.
- Consult your doctor for more details.
Storage
- Store the unmixed powder form at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
- Protect from high heat.
- After mixing, store at room temperature or in the refrigerator.
- Consult the package instructions or your pharmacist for other storage details.
- Keep all medicines away from children and pets.
How
To Use - This medication is given by injection into a vein as directed by your doctor.
- Dosage is based on your medical condition, body size, and response to treatment.Read and learn all preparation and usage instructions supplied by the manufacturer.
- Follow all instructions for proper handling and mixing with the correct IV fluids.
- Before using, check the product visually for particles or discoloration.
- If either is present, do not use the liquid.If this medication touches your skin, immediately wash the area well with soap and water.
- If this medication gets in your eye, open the eyelid and flush with water for 15 minutes, then seek immediate medical attention.Learn how to store and discard needles and medical supplies safely.
- Consult your pharmacist for details.To help prevent urinary problems, drink plenty of fluids and urinate frequently while using this medication unless otherwise directed by your doctor.
- Your doctor may also prescribe other medication (e.g., mesna, IV fluids) to decrease the risk.
Side
Effects - See also Warning section.Nausea, vomiting, diarrhea, stomach/abdominal pain, loss of appetite, or redness/pain/swelling at the injection site may occur.
- Nausea and vomiting can be severe.
- In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting.
- Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects.
- If these effects persist or worsen, tell your doctor or pharmacist promptly.Severe nausea, vomiting, and diarrhea may infrequently result in a loss of too much body water (dehydration).
- Contact your doctor promptly if you notice any symptoms of dehydration such as unusual decreased urination, unusual dry mouth/increased thirst, lack of tears, dizziness/lightheadedness, or pale/wrinkled skin.Temporary hair loss frequently occurs in patients using this drug.
- Normal hair growth should return after treatment has ended.Many people using this medication have serious side effects.
- However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects.
- Careful monitoring by your doctor may decrease your risk.Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual weakness, seizure.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before receiving ifosfamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood/bleeding disorders (e.g., anemia, low blood cell counts), current infection, kidney disease, liver disease, radiation treatment.Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.
- Wash your hands well to prevent the spread of infections.To lower your risk of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.Before having surgery, tell your doctor or dentist that you are using this medication.This drug may make you drowsy.
- Use caution while driving, using machinery, or taking part in any other activity that requires alertness.
- Limit alcoholic beverages.This medication may affect the production of sperm, increasing the risk of fathering a child with birth defects.
- Therefore, men receiving treatment with this drug should use reliable forms of birth control (e.g., condoms).
- Consult your doctor for details and to discuss effective forms of birth control.This medication is not recommended for use during pregnancy.
- It may harm an unborn baby.
- If you become pregnant or think you may be pregnant, tell your doctor immediately.
- To avoid pregnancy, both males and females using this drug should use reliable form(s) of birth control (e.g., birth control pills, condoms) during treatment.
- Consult your doctor for details and to discuss effective forms of birth control.This medication passes into breast milk and may have undesirable effects on a nursing infant.
- Therefore, breast-feeding is not recommended while using this drug.
- Consult your doctor before breast-feeding.
Missed
Dose - For the best possible benefit, it is important to receive each scheduled dose of this medication as directed.
- If you miss a dose, contact your doctor to establish a new dosing schedule.
- Do not double the dose to catch up.
Drug
Interactions - Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medication because very serious interactions may occur: nalidixic acid.If you are currently using the medication listed above, tell your doctor or pharmacist before starting ifosfamide.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: other anti-cancer drugs.
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CONDITIONS
OF USE: The information in this database is intended to supplement, not substitute
for, the expertise and judgement of healthcare professionals. The information
is not intended to cover all possible uses, directions, precautions, drug interactions
or adverse effects, nor should it be construed to indicate that use of a particular
drug is safe, appropriate or effective for you or anyone else. A healthcare professional
should be consulted before taking any drug, changing any diet or commencing or
discontinuing any course of treatment. |