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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Galsulfase Naglazyme Uses Improves walking ability in people with an enzyme deficiency called mucopolysaccharidosis VI (MPS VI), which can affect certain tissues in the body. Storage If you store this medicine at home, keep it in the refrigerator. Do not freeze. Before using this medicine, you may remove it from the refrigerator and allow it to warm to room temperature. If you do not use the medicine, put it back in the refrigerator. Do not use medicine that has been left at room temperature for longer than 24 hours. Never heat the medicine with hot water or in a microwave. Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Injectable. Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to. Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins. A nurse or other trained health professional will give you this medicine. The usual dose schedule for this medicine is one time each week. The medicine must be given slowly, so the needle will remain in place for at least 4 hours. An IV pump is sometimes used if the medicine needs to be given over several hours or throughout an entire day. You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to. Use a new needle and syringe each time you inject your medicine. Do not use the medicine if it has changed color or has particles in it. Do not shake the medicine. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Breathing that stops during sleep. Feeling very drowsy or sleepy. Fever or chills. Lightheadedness or fainting. Precautions You should not receive this medicine if you have had an allergic reaction to galsulfase. Missed Dose Call your doctor or pharmacist for instructions. Drug Interactions Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you snore or have sleep apnea. Galsulfase can cause fever and allergic-type reactions. You will receive medicine to prevent these effects, and that medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. Some of the side effects of galsulfase may not occur for several weeks after you start using the medicine.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.