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Drug Guide    C   Cotrim I.V.

  Prescription drug information   Post your opinion about this drug  

   Cotrim I.V.

Cotrim I.V.
IV


This medication is used to treat a wide variety of bacterial infections. It is also used to treat a certain type of pneumonia (pneumocystis pneumonia) in patients with a weakened immune system. This medication is a combination of 2 antibiotics, sulfamethoxazole and trimethoprim. It works by stopping the growth of bacteria and the pneumocystis fungus.This medication treats only certain types of infections. It will not work for viral infections (e.g., flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

 
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 Cotrim I.V. images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Cotrim I.V.

Uses
This medication is used to treat a wide variety of bacterial infections. It is also used to treat a certain type of pneumonia (pneumocystis pneumonia) in patients with a weakened immune system. This medication is a combination of 2 antibiotics, sulfamethoxazole and trimethoprim. It works by stopping the growth of bacteria and the pneumocystis fungus.This medication treats only certain types of infections. It will not work for viral infections (e.g., flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
Notes
  • Do not share this medication with others.This medication has been prescribed for your current condition only.
  • Do not use it later for another infection unless told to do so by your doctor.
  • A different medication may be necessary in that case.If you are using this medication for an extended period, laboratory and/or medical tests (e.g., complete blood count, kidney function tests, potassium blood level, blood cultures) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store the unmixed vials and mixed solution at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not refrigerate.
  • Use opened multi-dose vials within 48 hours.
  • Consult your pharmacist about how long you can use the medication after it is mixed.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: dizziness, drowsiness, confusion, depression, blood in the urine, loss of consciousness.

How To Use
  • This medication is given by injection into a vein as directed by your doctor.
  • It must not be injected into a muscle.
  • This medication must be properly mixed with the correct IV fluids (dextrose 5 percent solution) and given by slow infusion over 60-90 minutes.Before using, check this product visually for particles, cloudiness, and discoloration.
  • If any of these are present, do not use the liquid.Drink plenty of fluids during treatment with this medication unless your doctor advises you otherwise.
  • This will help prevent unlikely side effects, such as crystals appearing in the urine and kidney stones.
  • The dosage is based on your medical condition, weight, and response to therapy.Antibiotics work best when the amount of medicine in your body is kept at a constant level.
  • Therefore, give this drug at evenly spaced intervals throughout the day and night.Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days.
  • Stopping the medication too early may result in a return of the infection.Inform your doctor if your condition persists or worsens.

Side Effects
  • Nausea, vomiting, diarrhea, loss of appetite, or headache may occur.
  • If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: pain/redness/swelling at the injection site, sun sensitivity (sunburn), muscle weakness, mental/mood changes (e.g., depression, hallucinations), crystals in the urine, painful urination, change in the amount of urine, lump/growth/swelling in the front of the neck (goiter), signs of low blood sugar (e.g., shaking, dizziness, blurred vision, unusual hunger).Seek immediate medical attention if any of these rare but very serious side effects occur: confusion, persistent/severe headache, neck stiffness, seizures.This medication may rarely cause serious (possibly fatal) allergic reactions and other side effects such as a severe peeling skin rash (e.g., Stevens-Johnson syndrome), blood disorders (e.g., agranulocytosis, aplastic anemia), liver damage, or lung injury.
  • Seek immediate medical attention if you notice any of the following: skin rash/blisters, itching, swelling, severe dizziness, persistent cough, trouble breathing, signs of a new infection (e.g., persistent sore throat, fever), pale skin, easy bleeding/bruising, yellowing eyes/skin, persistent nausea/vomiting, unusual tiredness, dark urine, stomach/abdominal pain, joint pain.This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a type of resistant bacteria.
  • This condition may occur while receiving therapy or even weeks after treatment has stopped.
  • Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse.
  • Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection.
  • Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using sulfamethoxazole with trimethoprim injection, tell your doctor or pharmacist if you are allergic to it; or to sulfa medications; or to sodium metabisulfite; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: a certain blood disorder (anemia due to folate vitamin deficiency), a certain metabolic disorder (porphyria).Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, severe allergies, asthma, diabetes, other blood disorders, decreased bone marrow function (bone marrow suppression), a certain other metabolic disorder (G6PD deficiency), conditions that put you at risk for folate vitamin deficiency (e.g., chronic alcohol use, anti-seizure medication use, intestinal absorption problems, malnutrition).This medication may make you more sensitive to the sun.
  • Avoid prolonged sun exposure, tanning booths, and sunlamps.
  • Use a sunscreen and wear protective clothing when outdoors.This medication should not be used in infants younger than 2 months.
  • However, if the decision is made to use this medication in newborn infants, it should be known that a preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product can infrequently cause serious (sometimes fatal) problems if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life.
  • The risk is also greater with low-birth-weight infants.
  • Symptoms include sudden gasping, low blood pressure, very slow heartbeat.
  • If you notice any of these symptoms in your newborn, report them to the doctor immediately.
  • If possible, a preservative-free product should be used when treating newborns.Kidney function declines as you grow older.
  • This medication is removed by the kidneys.
  • Therefore, the elderly may be more sensitive to the side effects of the drug, especially skin reactions and blood disorders.Patients with AIDS may be more sensitive to the side effects of the drug, especially skin reactions, fever, and blood disorders.During pregnancy, this medication should be used only when clearly needed.
  • This medication should not be used near the expected delivery date because of possible harm to the unborn baby.
  • Discuss the risks and benefits with your doctor.This drug passes into breast milk.
  • While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency).
  • Therefore, breast-feeding is not recommended in infants with these conditions.
  • Consult your doctor before breast-feeding any infant.

Missed Dose
  • If you miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: dofetilide, methenamine.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting sulfamethoxazole with trimethoprim.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: certain anti-diabetic medications (sulfonylureas such as glipizide, glyburide, tolbutamide), cyclosporine, digoxin, hydantoins (e.g., phenytoin), live bacterial vaccines, methotrexate, PABA taken by mouth, procainamide, pyrimethamine, tricyclic antidepressants (e.g., amitriptyline), warfarin, certain "water pills" (thiazide diuretics such as hydrochlorothiazide), drugs that can increase potassium levels (e.g., potassium supplements, ACE inhibitors such as captopril and lisinopril).This medication may decrease the effectiveness of combination-type birth control pills.
  • This can result in pregnancy.
  • Ask your doctor or pharmacist for details.
  • Discuss whether you should use additional reliable birth control methods while using this medication.This product can affect the results of certain lab tests.
  • Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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