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Drug Guide    C   Caine-2

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This medication is used for numbing an area of skin or part of the body just before surgery. Lidocaine belongs to a class of drugs known as anesthetics. It works by blocking pain signals, allowing certain surgical procedures to be done without putting you under general anesthesia (to sleep).

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OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions

This medication is used for numbing an area of skin or part of the body just before surgery. Lidocaine belongs to a class of drugs known as anesthetics. It works by blocking pain signals, allowing certain surgical procedures to be done without putting you under general anesthesia (to sleep).
  • Laboratory and/or medical tests (e.g., breathing rate, EKG, heart rate) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

  • Store vials, ampules, and syringes at room temperature between 59-86 degrees F (15-30 degrees C) away from light.
  • Keep all medicines away from children and pets.

  • If overdose is suspected, your doctor is trained to manage your condition.
  • Symptoms of overdose may include: slow heartbeat, vomiting, feelings of heat or cold, twitching, shakiness, seizures, fainting, slow/stopped breathing.

How To Use
  • This medication is given by either a doctor or dentist in the office or by an anesthesia doctor (anesthesiologist) in the hospital.
  • This medication is given by injection into the skin or around a nerve or by slow injection around the spinal cord, depending on the amount of numbing that is needed for your surgery.
  • Other medicines may be used with lidocaine if needed.Before using, check this product visually for particles or discoloration.
  • If either is present, do not use the liquid.A small test dose may be given first to see how you respond to this medication.Dosage is based on your age, liver function, medical condition, response to treatment, and type of surgery.If you are awake during your surgery, tell your doctor immediately if you feel pain.

Side Effects
  • See also Overdose section.The side effects of lidocaine injection depend on how it is used.
  • Injecting lidocaine into the skin will cause temporary stinging/burning.
  • Injection around the spinal cord (e.g., spinal, epidural anesthesia) may also cause temporary loss of muscle control.
  • Less common side effects may include headaches, backache, and shivering.
  • If any of these effects persist or worsen, tell your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.The following uncommon side effects usually only occur with higher doses of lidocaine injected around the spinal cord but may occur with numbing of smaller areas of skin if you have severe liver problems.
  • Tell your doctor immediately if any of these unlikely but serious side effects occur: lightheadedness, nervousness, ringing in the ears, unusual pleasurable feelings/mood, confusion, dizziness, drowsiness, nausea, decreased breathing, double vision.Tell your doctor immediately if any of these rare but very serious side effects occur with injection around the spinal cord: persistent loss of bowel/bladder control, persistent numbness in the groin or anal areas, persistent loss of sexual ability.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, tell your doctor immediately.

  • Before receiving lidocaine for injection, tell your doctor or pharmacist if you are allergic to it; or to certain preservatives (e.g., methylparaben); or to sulfites; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease (e.g., chronic hepatitis, cirrhosis), severe shock due to the heart not pumping well (e.g., very low blood pressure and loss of consciousness), other heart problems (e.g., heart failure, previous heart attack), a certain abnormal heartbeat (heart block).Before receiving this medication as an injection around the spinal cord, tell your doctor or pharmacist your medical history, especially of: conditions of the nerves/spinal chord/brain (e.g., seizures, multiple sclerosis, abnormal shape of the spine), severe blood infection (sepsis), severe high blood pressure.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially the nerve, heart, and blood pressure effects.
  • Lower doses are usually recommended.Caution is advised when using this drug in children because they may be more sensitive its effects.
  • Lower doses should be used.If lidocaine is used with epinephrine/norepinephrine for skin numbing, caution should be used if you have certain blood vessel diseases (e.g., peripheral vascular disease, hypertensive vascular disease).During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.
  • Lidocaine used during childbirth may rarely cause side effects in your newborn.
  • Consult your doctor for more information.It is not known whether this drug passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • Not applicable.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: disopyramide, dofetilide, halofantrine, pimozide, arbutamine.If you are currently using any of these medications listed above, tell your doctor or pharmacist before receiving lidocaine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amprenavir, fosamprenavir, beta blockers (e.g., propranolol, atenolol), cimetidine, drugs for heart rhythm problems (e.g., amiodarone, procainamide), succinylcholine.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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