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Drug Guide    A   Arthrogesic

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   Arthrogesic

Arthrogesic
Oral


This combination medication is used to reduce pain, swelling, and joint stiffness from conditions such as arthritis. Magnesium salicylate is known as a nonsteroidal anti-inflammatory drug (NSAID). Phenyltoloxamine is known as an antihistamine.

 
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 Arthrogesic images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Arthrogesic

Uses
This combination medication is used to reduce pain, swelling, and joint stiffness from conditions such as arthritis. Magnesium salicylate is known as a nonsteroidal anti-inflammatory drug (NSAID). Phenyltoloxamine is known as an antihistamine.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., liver and kidney function test, complete blood count, blood pressure) may be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.If you have arthritis, lifestyle changes (e.g., weight loss if needed, strengthening/conditioning exercises) may help improve your flexibility and joint function.
  • Consult your doctor for specific instructions.

Storage
  • Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: dizziness, ringing in the ears, weakness, nausea, vomiting, severe drowsiness, fast breathing, confusion, seizures.

How To Use
  • Take this medication by mouth, usually 3 to 4 times daily with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor.
  • Do not lie down for at least 30 minutes after taking this drug.
  • If stomach upset occurs while taking this medication, take it with food, milk, or an antacid.Dosage is based on your medical condition and response to treatment.
  • To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time.
  • Do not increase your dose, take it more frequently, or take it for a longer time than prescribed.
  • For ongoing conditions such as arthritis, continue taking this medication as directed.
  • Discuss the risks and benefits with your doctor or pharmacist.For certain conditions (e.g., arthritis), it may take up to 2 weeks of taking this drug regularly until you get the full benefit.If you are taking this drug "as needed" (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur.
  • If you wait until the symptoms have worsened, the medicine may not work as well.Tell your doctor if your condition does not improve or if it worsens.

Side Effects
  • See also Warning section.Dizziness, drowsiness, constipation, nausea, stomach upset, heartburn, blurred vision, or dry mouth/nose/throat may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if you have any of these unlikely but serious side effects: stomach pain, swelling of ankles/feet/hands, sudden/unexplained weight gain, difficulty urinating, mental/mood changes, hearing changes (e.g., ringing in the ears, decreased hearing), vision changes.Stop taking this medication and tell your doctor immediately if any of these rare but very serious side effects occur: fast/pounding/irregular heartbeat, change in the amount of urine, easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), yellowing eyes/skin, dark urine, unusual tiredness, persistent nausea/vomiting.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other side effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking this medication, tell your doctor or pharmacist if you are allergic to magnesium salicylate or phenyltoloxamine; or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, salsalate); or to other antihistamines (e.g., diphenhydramine); or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease.Before using this medication, tell your doctor or pharmacist your medical history, especially of: aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), kidney disease, liver disease, heart disease (e.g., heart failure, history of heart attack), stroke, overactive thyroid gland (hyperthyroidism), bleeding/clotting problems, glaucoma, stomach/intestine/esophagus problems (e.g., bleeding, ulcers, recurring heartburn, blockage), high blood pressure, diabetes, seizure, difficulty urinating (e.g., due to enlarged prostate gland), breathing problems (e.g., asthma, chronic obstructive pulmonary disease-COPD), swelling of the ankles/feet/hands, a severe loss of body water (dehydration), blood disorders (e.g., anemia), certain genetic conditions (G6PD deficiency, pyruvate kinase deficiency), growths in the nose (nasal polyps), mental/mood disorders.Before having surgery, tell your doctor or dentist that you are using this medication.This drug may make you dizzy or drowsy or cause blurred vision.
  • Use caution while driving, using machinery, or taking part in any other activity that requires alertness or clear vision.
  • Avoid alcoholic beverages because they may increase the risk of this drug's side effects.This medicine may cause stomach bleeding.
  • Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding.
  • Avoid alcohol and stop smoking.
  • Consult your doctor or pharmacist for more information.Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially stomach bleeding and dizziness.This medicine contains magnesium salicylate, which is similar to aspirin.
  • Children and teenagers should not take this medication if they have chickenpox, flu, or any undiagnosed illness, or if they have just been given a live virus vaccine, without first consulting a doctor about Reye's syndrome, a rare but serious illness.Caution is advised when using this drug in children because they are more sensitive to the effects of antihistamines.
  • This drug can often cause excitement in young children instead of drowsiness.During the first 6 months of pregnancy, this medication should be used only when clearly needed.
  • It is not recommended for use during the last 3 months of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.
  • Discuss the risks and benefits with your doctor.This medication passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you are taking this drug on a regular schedule (not "as needed") and you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: cidofovir, ketorolac.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergics (e.g., atropine, scopolamine), anti-platelet drugs (e.g., cilostazol, clopidogrel), "blood thinners" (e.g., enoxaparin, heparin, warfarin), carbonic anhydrase inhibitors (e.g., acetazolamide), certain diabetes drugs (sulfonylureas such as glyburide), certain drugs for seizures (phenytoin, phenobarbital, valproic acid), corticosteroids (e.g., prednisone), cyclosporine, drugs for gout (e.g., probenecid, sulfinpyrazone), drugs for high blood pressure (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta blockers such as metoprolol), gabapentin, lithium, other drugs that contain magnesium (e.g., milk of magnesia), MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), methotrexate, bisphosphonates taken by mouth (e.g., alendronate), pemetrexed, SSRI antidepressants (e.g., fluoxetine, sertraline), tenofovir, tricyclic antidepressants (e.g., amitriptyline), "water pills" (diuretics such as furosemide, hydrochlorothiazide, spironolactone).Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as certain antihistamines (e.g., diphenhydramine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., risperidone, trazodone).Check all prescription and nonprescription medicine labels carefully since they may contain drowsiness-causing ingredients or pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that are similar to this drug and, if taken together, may increase your risk for side effects.
  • Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day).
  • Consult your doctor or pharmacist for more details.Some medications (e.g., ciprofloxacin, tetracycline) must not be taken with magnesium.
  • The magnesium in this product may react with these medications, preventing their full absorption.
  • Take these other medications 2 to 3 hours before or after taking this medication.
  • Ask your pharmacist for more details.This medication may interfere with certain laboratory tests (including certain urine glucose tests, skin tests), possibly causing false test results.
  • Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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