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Drug Guide    A   Anagrelide

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   Anagrelide

Anagrelide
Oral


Anagrelide is used to treat a certain blood disorder (thrombocythemia), which is caused by your bone marrow making too many platelets. Platelets are a blood cell that the body uses to form blood clots. Too many platelets can cause problems with your circulation, including unwanted blood clots and bleeding problems. This drug reduces the number of platelets in the bloodstream by blocking their production.

 
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 Anagrelide images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Anagrelide

Uses
Anagrelide is used to treat a certain blood disorder (thrombocythemia), which is caused by your bone marrow making too many platelets. Platelets are a blood cell that the body uses to form blood clots. Too many platelets can cause problems with your circulation, including unwanted blood clots and bleeding problems. This drug reduces the number of platelets in the bloodstream by blocking their production.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., complete blood counts, kidney and liver function tests) should be performed periodically to monitor your progress or check for side effects.
  • Consult your doctor for more details.

Storage
  • Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
  • Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: unusual bleeding, bruising.

How To Use
  • Take this medication by mouth with or without food, usually 2 or 4 times a day or as directed by your doctor.
  • Children or people with liver problems may start out by taking only 1 dose each day.
  • Your doctor will adjust your dose, usually once a week, to find the best dose for you that keeps your blood counts closer to normal.
  • The dosage is based on your medical condition and response to therapy.
  • You should not take more than 2.5 milligrams in a single dose or more than a total of 10 milligrams in a day.Use this medication regularly in order to get the most benefit from it.
  • To help you remember, take it at the same times each day.
  • It is important to continue taking this medication even if you feel well.
  • People with high platelets may not feel sick.
  • Do not stop taking this medication without consulting your doctor.
  • Stopping anagrelide will cause your platelets to go back up.Your doctor will check your blood counts regularly to monitor your progress and adjust your dose.

Side Effects
  • Headache, diarrhea, weakness, nausea, and dizziness may occur.
  • If any of these effects persist or worsen, contact your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual bleeding/bruising, black stools, swelling of the ankles/feet, rapid/difficult breathing, fainting, stomach/abdominal pain, unusual tiredness, change in the amount of urine, pink/bloody urine, vomit that looks like coffee grounds.Seek immediate medical attention if any of these rare but very serious side effects occur: chest/jaw/left arm pain, confusion/mental changes, fast/irregular/pounding heartbeat, slurred speech, vision changes, weakness on one side of the body.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
  • Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing..If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before taking anagrelide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
  • Before using this medicine, consult your doctor or pharmacist if you have: severe liver disease.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., heart attack, heart failure, irregular heartbeat), kidney problems, liver problems.This drug may make you dizzy; use caution while engaging in activities requiring alertness such as driving or using machinery.
  • Limit alcoholic beveragesTo avoid dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Before having surgery, tell your doctor or dentist that you are using this medication.This medication is not recommended for use during pregnancy because of possible harm to the unborn baby.
  • Discuss the risk and benefits with your doctor.
  • If you become pregnant or think you may be pregnant, inform your doctor immediately.
  • Consult your doctor for more details and to discuss reliable forms of birth control.This drug may pass into breast milk and could have undesirable effects on a nursing infant.
  • Therefore, breast-feeding is not recommended while using this drug.
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, take it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop or change the dosage of any medicine before checking with them first.Tell your doctor of all nonprescription and prescription medication you may use, especially of: sucralfate.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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