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Drug Guide    A   Aminophyllin

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   Aminophyllin

Aminophyllin
Oral


This medication is used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g., asthma, emphysema, chronic bronchitis). Aminophylline belongs to a class of drugs known as xanthines. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs' response to irritants. Controlling symptoms of breathing problems can decrease time lost from work or school.This medication does not work immediately and should not be used for sudden attacks of breathing trouble. Your doctor should prescribe a quick-relief medicine/inhaler (e.g., albuterol) for sudden attacks of shortness of breath/asthma while you are on this medication. You should always have a quick-relief inhaler with you. Consult your doctor or pharmacist for more details.

 
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 Aminophyllin images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Aminophyllin

Uses
This medication is used to treat and prevent wheezing and trouble breathing caused by ongoing lung disease (e.g., asthma, emphysema, chronic bronchitis). Aminophylline belongs to a class of drugs known as xanthines. It works in the airways by relaxing muscles, opening air passages to improve breathing, and decreasing the lungs' response to irritants. Controlling symptoms of breathing problems can decrease time lost from work or school.This medication does not work immediately and should not be used for sudden attacks of breathing trouble. Your doctor should prescribe a quick-relief medicine/inhaler (e.g., albuterol) for sudden attacks of shortness of breath/asthma while you are on this medication. You should always have a quick-relief inhaler with you. Consult your doctor or pharmacist for more details.
Notes
  • Do not share this medication with others.Laboratory and/or medical tests (e.g., theophylline blood levels) should be performed periodically to monitor your progress or check for side effects.
  • It is important that you do not miss your medication or take extra doses for 2-3 days before your theophylline blood levels are checked.
  • Consult your doctor for more details.

Storage
  • Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
  • Do not store in the bathroom.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: agitation, nausea, frequent vomiting, trouble sleeping, unusual thirst, fever, ringing in the ears, seeing flashes of light, fast/irregular heartbeat, seizures, confusion.

How To Use
  • Take this medication by mouth with or without food, usually 2 to 4 times daily or as directed by your doctor.
  • If this medicine upsets your stomach, you may take it with food.If you have long-acting tablets, you may break them in half and swallow with water.
  • Do not chew or crush the tablets.
  • Doing so can destroy the long action of the drug and may increase side effects.Dosage is based on your medical condition, response to therapy, age, weight, drug blood levels, and other drugs you may be taking.
  • (See also Drug Interactions section.)Use this medication regularly to get the most benefit from it.
  • To help you remember, take it at the same times each day.Inform your doctor if your condition persists or worsens.

Side Effects
  • Stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking (tremors), flushing, and increased urination may occur.
  • If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: confusion, dizziness, mental/mood changes, muscle twitching/pain/tenderness, weakness, rapid breathing.Tell your doctor immediately if any of these rare but very serious side effects occur: chest pain, fainting, fast/slow/irregular heartbeat, dark/tarry stools, vomit that looks like coffee grounds, seizures.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, red/scaly skin, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
  • Before using aminophylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine, caffeine, or ethylenediamine; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain breathing disorder (cystic fibrosis), diabetes, glaucoma, heart problems (e.g., congestive heart failure, irregular heartbeat), high blood pressure, kidney disease, liver disease (e.g., cirrhosis), seizures, stomach/intestinal ulcer, thyroid disease.This drug may make you dizzy.
  • Use caution while driving, using machinery, or doing any activity that requires alertness.
  • Limit alcoholic beverages.If you develop a fever/flu-like symptoms while taking this medication, tell your doctor promptly.
  • The dose of your medicine may need to be adjusted.Before having surgery, tell your doctor or dentist that you are taking this medication.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects.
  • Careful monitoring of side effects and drug blood levels is recommended.Caution is advised when using this drug in children because they may be more sensitive to its effects.
  • Careful monitoring of side effects, drug blood levels, and dose adjustment is recommended.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.
  • Blood levels may change during the last 3 months of pregnancy.
  • Careful monitoring of side effects, drug blood levels, and dose adjustment is recommended.This drug passes into breast milk and may have undesirable effects on a nursing infant (e.g., irritability).
  • Consult your doctor before breast-feeding.

Missed Dose
  • If you miss a dose, skip the missed dose and resume your usual dosing schedule.
  • Do not double the dose to catch up.

Drug Interactions
  • Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
  • Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: adenosine, adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine), allopurinol, aminoglutethimide, certain antiarrhythmic drugs (e.g., mexiletine, propafenone), anti-seizure drugs (e.g., carbamazepine, phenytoin, phenobarbital), benzodiazepines (e.g., diazepam, flurazepam), certain beta blockers (e.g., propranolol), birth control pills, cimetidine, digoxin, disulfiram, fluvoxamine, interferon, macrolide antibiotics (e.g., erythromycin, clarithromycin), isoproterenol, lithium, methotrexate, moricizine, pentoxifylline, certain quinolones (e.g., ciprofloxacin, enoxacin), rifampin, St John's wort, sulfinpyrazone, tacrine, thiabendazole, ticlopidine, verapamil, zileuton.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase the side effects of this medication.
  • Ask your pharmacist about using those products safely.Tobacco/marijuana smoking decreases blood levels of this medication.
  • Tell your doctor if you smoke or have recently stopped smoking.
  • Your dose of medication may need to be adjusted.Caffeine and alcohol can increase the side effects of this medication.
  • Avoid drinking large amounts of beverages containing alcohol or caffeine (e.g., coffee, tea, colas) or eating large amounts of chocolate.Certain diets (e.g., high protein/low carbohydrate or high carbohydrate/low protein) may change the effect of aminophylline.
  • Tell your doctor if you are following a dietary plan or eat beef every day.
  • The dose of your medicine may need to be adjusted.This medication may interfere with certain laboratory tests (e.g., blood sugar, cholesterol, uric acid, dipyridamole-thallium imaging tests), possibly causing false test results.
  • Make sure laboratory personnel and all your doctors know you use this drug.Laboratory tests for drug blood levels may be affected by other drugs/foods, possibly causing false test results.
  • Tell laboratory personnel and all your doctors if you take or use any of the following products: caffeine, theobromine, chocolate, furosemide, sulfathiazole, phenylbutazone, probenecid, acetaminophen, cefazolin, cephalothin.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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