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Drug Guide    A   Alendronate/cholecalciferol

  Prescription drug information   Post your opinion about this drug  


(oral) (tablet)

Treats osteoporosis in postmenopausal women. Also increases bone mass in men who have osteoporosis.


Fosamax Plus D
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 Alendronate/cholecalciferol images:

OverviewPhotosHow To UseSide EffectsPrecautionsMissed DoseDrug Interactions
Fosamax Plus D
Treats osteoporosis in postmenopausal women. Also increases bone mass in men who have osteoporosis.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed. Keep all medicine away from children and never share your medicine with anyone.

How To Use
  • APPEARANCE: Tablet. Your doctor will tell you how much of this medicine to use and how often.
  • Do not use more medicine or use it more often than your doctor tells you to. You must take this medicine first thing in the morning, right after you get out of bed and before you eat or drink anything. Swallow this medicine with a full glass of water (6 to 8 ounces).
  • Plain tap water is the only liquid you should use to take this medicine.
  • Avoid coffee, juice, soft drinks, mineral water, or any other type of beverage.
  • These other liquids can change the way your body absorbs the medicine, making it less effective. Swallow the tablet whole.
  • Do not crush, break, or chew it. To protect your esophagus from irritation, do not lie down or bend over for at least 30 minutes after taking the medicine.
  • If you sit down, keep your upper body as upright as possible.
  • Do not eat or drink anything, or take any other medicines or supplements for at least 30 minutes after taking this medicine. This medicine comes with patient instructions.
  • Read and follow these instructions carefully.
  • Ask your doctor or pharmacist if you have any questions.

Side Effects
  • Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Burping or belching that causes burning in your throat. Heartburn or pain behind your breastbone. Pain when you swallow. Severe bone, joint, or muscle pain.

  • You should not use this medicine if you have had an allergic reaction to alendronate or a vitamin D supplement.
  • You should not use this medicine if you have trouble swallowing, or if you cannot stand or sit upright for at least 30 minutes at a time.
  • You should not use this medicine if you have low levels of calcium in your blood (hypocalcemia).

Missed Dose
  • This medicine is usually taken one time per week.
  • If you miss your regularly scheduled dose or you forget to take your medicine, wait until the next morning to take it.
  • Do not use extra medicine to make up for a missed dose.
  • You should never take two tablets in one day.

Drug Interactions
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease. This medicine can irritate your esophagus (the tube that runs from your throat to your stomach).
  • Tell your doctor if you have any condition that affects your stomach, your esophagus, or your digestion. Your doctor should know if you have any type of vitamin or mineral deficiency or imbalance. Your doctor may instruct you to take extra calcium or vitamin D supplements.
  • Carefully follow your doctor's instructions about taking this medicine with other supplements.
  • Taking too much vitamin D can be harmful. Your doctor may recommend weight-bearing exercise or diet changes to further decrease your risk of osteoporosis.
  • Smoking cigarettes and drinking alcohol can increase your risk of osteoporosis, so it is best to avoid these things.

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Low adverse Reactions
Healing Power
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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